Evidence map›Paper›PMID 30214584›Full record

ArticleOncology letters2018

Influence of SLCO1B1 in gastric cancer patients treated with EOF chemotherapy.

Wanjing Feng, Xin Liu, Xiaoying Zhao, Mingzhu Huang, Weijian Guo, Jiliang Yin, Zhiyu Chen, Xiaodong Zhu

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncology letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Wanjing FengDepartment of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, P.R. China.
Xin LiuDepartment of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, P.R. China.
Xiaoying ZhaoDepartment of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, P.R. China.
Mingzhu HuangDepartment of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, P.R. China.
Weijian GuoDepartment of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, P.R. China.
Jiliang YinDepartment of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, P.R. China.
Zhiyu ChenDepartment of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, P.R. China.
Xiaodong ZhuDepartment of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, P.R. China.
Fudan University Shanghai Cancer Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytochrome-P450 enzymes, ATP-binding cassette transporters, and solute carriers mediate drug metabolism as metabolic enzymes and membrane transporters, respectively. The present study investigated whether single nucleotide polymorphisms (SNPs) in genes encoding these proteins were predictive or prognostic factors in patients with metastatic gastric cancer (MGC) undergoing chemotherapy. A retrospective study of 108 MGC patients who received epirubicin, oxaliplatin, and 5-fluorouracil (EOF) as first-line treatment was performed. A total of 13 SNPs were genotyped, including

Indexed as

and 5-fluorouracil regimengastric canceroxaliplatinreceived epirubicinsingle nucleotide polymorphismSLCO1B1

Identifiers

PMID30214584
PMCPMC6126332
OpenAlexW2883660451

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.