Evidence map›Paper›PMID 30214471›Full record

ArticleChinese medicine2018

Characterization and anti-tumor activity of a polysaccharide isolated from

Yuan Wei, Linwei Wang, Dujun Wang, Dan Wang, Chongwei Wen, Bangxin Han, Zhen Ouyang

Open access · goldAbstract read
In one paragraph

Article in Chinese medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 50 citations in OpenAlex.

  1. Orchid genome evolution and trait innovation.Journal of integrative plant biology · 2026
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  8. Research Progress on the Anticancer Activity of Plant Polysaccharides.Recent patents on anti-cancer drug discovery · 2024
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  12. Glucomannan inGenes · 2022
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  14. Bioactivities and Mechanism of Actions ofOxidative medicine and cellular longevity · 2022
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  15. Quality Markers ofFrontiers in nutrition · 2022
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  16. Review
  17. Evidence-based complementary and alternative medicine : eCAM · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yuan Wei1School of Pharmacy, Jiangsu University, 301 Xuefu Road, Zhenjiang, 212013 Jiangsu China.ORCID 0000-0002-4025-6567
Linwei Wang1School of Pharmacy, Jiangsu University, 301 Xuefu Road, Zhenjiang, 212013 Jiangsu China.
Dujun Wang1School of Pharmacy, Jiangsu University, 301 Xuefu Road, Zhenjiang, 212013 Jiangsu China.
Dan Wang1School of Pharmacy, Jiangsu University, 301 Xuefu Road, Zhenjiang, 212013 Jiangsu China.
Chongwei Wen1School of Pharmacy, Jiangsu University, 301 Xuefu Road, Zhenjiang, 212013 Jiangsu China.
Bangxin Han2School of Biological and Pharmaceutical Engineering, West Anhui University, Lu'an, 237012 China.
Zhen Ouyang1School of Pharmacy, Jiangsu University, 301 Xuefu Road, Zhenjiang, 212013 Jiangsu China.
Jiangsu University · CNWest Anhui University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPolysaccharides are carbohydrate chains composed of linked monosaccharide units. Accumulating studies report that polysaccharides isolated from

methodsA polysaccharide (DOPA-1) was isolated from

resultsOur results show that DOPA-1 is mainly comprised of mannose, glucose, and galactose at a molar ratio of 1:0.42:0.27 and has an average molecular weight of 2.29 × 10

conclusionsOur findings suggest that DOPA-1 induces apoptosis in tumor cells via altered mitochondrial function, ROS production, and altered apoptosis-related protein expression. This bioactive polysaccharide could, therefore, potentially be further developed as an anti-tumor adjuvant drug.

Indexed as

Anti-tumor effectApoptosisDendrobium officinaleHuoshan areaPolysaccharide characterization

Identifiers

PMID30214471
PMCPMC6131812
OpenAlexW2891962273

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.