Evidence map›Paper›PMID 30214306›Full record

ArticleCancer management and research2018

Association between lncRNA CASC8 polymorphisms and the risk of cancer: a meta-analysis.

Zhigang Cui, Min Gao, Zhihua Yin, Lei Yan, Lei Cui

Abstract read
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In one paragraph

Article in Cancer management and research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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  19. Cancer management and research · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhigang CuiDepartment of Medical Informatics, China Medical University, Shenyang, People's Republic of China, lcui@cmu.edu.cn.
Min GaoDepartment of Epidemiology, School of Public Health, China Medical University, Shenyang, People's Republic of China.
Zhihua YinDepartment of Epidemiology, School of Public Health, China Medical University, Shenyang, People's Republic of China.
Lei YanDepartment of Medical Informatics, China Medical University, Shenyang, People's Republic of China, lcui@cmu.edu.cn.
Lei CuiDepartment of Medical Informatics, China Medical University, Shenyang, People's Republic of China, lcui@cmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the relationship between single-nucleotide polymorphisms (SNPs) in one of the long noncoding RNA (lncRNA), cancer susceptibility candidate 8 ( MATERIALS AND

methodsA meta-analysis was conducted to summarize the relationship between common SNPs (rs10505477 and rs7837328) in the lncRNA

resultsFifteen articles containing 20 datasets (24,504 cases and 22,969 controls) were finally included in the meta-analysis. Compared to the individuals carrying the rs10505477 TT genotype, those with the TC or CC genotype had a decreased risk of cancer (TC vs TT: OR 0.876, 95% CI 0.832-0.923,

conclusionThe rs10505477 and rs7837328 polymorphisms might be associated with risk of cancer.

Indexed as

cancerCASC8lncRNAmeta-analysissingle-nucleotide polymorphism

Identifiers

PMID30214306
PMCPMC6124472

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.