ReviewJournal of pain research2018
Current pain management strategies for patients with erythromelalgia: a critical review.
Review in Journal of pain research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Comparative Efficacy and Tolerability of Treatments for Erythromelalgia: A Systematic Review.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Non-specific cutaneous lupus erythematosus and clinical significance: a literature review.Journal of rheumatic diseases · 2026Review
- Erythromelalgia: Pathophysiology and Clinical Treatment Options, a Narrative Review.Current pain and headache reports · 2026Review
- Pediatric erythromelalgia from multidisciplinary perspectives: a scoping review.Pediatric research · 2025Article
- Article
- Acrocyanosis: The Least Known Acrosyndrome Revisited With a Dermatologic Perspective.Dermatology research and practice · 2025Review
- Mimicking the Usual Suspects: Erythromelalgia in the Differential Diagnosis.Journal of Brown hospital medicine · 2025Article
- Mepyramine targets mutant Nav1.7 channels to relieve pain and erythema in primary erythromelalgia patients.Frontiers in medicine · 2025Article
- Hyper-dilute botulinum toxin as an effective treatment for refractory erythromelalgia.JAAD case reports · 2024Article
- Successful Administration of Kampo Medicine and Acupuncture Treatment to Improve Erythromelalgia: A Case Report.Cureus · 2024Article
- Studying Erythromelalgia Using Doppler Flowmetry Perfusion Signals and Wavelet Analysis-An Exploratory Study.Biomedicines · 2023Article
- Clinical Characterization of Pediatric Erythromelalgia: A Single-Center Case Series.Children (Basel, Switzerland) · 2023Article
- Erythromelalgia in a patient with feet erythema and cyanosis.BMJ case reports · 2023Article
- A case of erythromelalgia with gastrointestinal dysautonomia treated with immunoglobulin: A case report.SAGE open medical case reports · 2023Article
- A Review of the Therapeutic Targeting of SCN9A and Nav1.7 for Pain Relief in Current Human Clinical Trials.Journal of pain research · 2023Review
- Case report: Spinal cord stimulation in the treatment of pediatric erythromelalgia.Frontiers in neurology · 2023Article
- Erythromelalgia presenting with body pain.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2022Article
- Title: Novel Analgesic Potential of ß2-Agonists for Neuropathic Pain via ß2-Agonist Action.Current pain and headache reports · 2022Review
- Auricular erythermalgia showing excellent response to itraconazole: a case report.Therapeutic advances in chronic disease · 2022Article
- Fish Oil and BCQ™ as a Novel Treatment Approach to Primary Erythromelalgia: A Case Study.Integrative medicine (Encinitas, Calif.) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Erythromelalgia (EM) is a rare disorder characterized by erythematous, warm, painful extremities, which is often precipitated by cold conditions. The pathophysiology of EM is incompletely understood. Recent investigations have identified sodium channelopathy as a genetic cause for this pain condition, classified as primary inherited EM. Other subtypes are idiopathic EM and secondary EM. The management of pain in EM is challenging as no single therapy has been found to be effective. There is varying response to pharmacotherapy and significant variability within this clinical population, resulting in a stepwise trial and error approach. Consequently, EM is often associated with poorer health-related quality of life with higher morbidity. There is currently no consensus or guidelines on management of pain in EM. This is a review of the literature on management of pain using pharmacologic, procedural intervention and nonpharmacologic treatment in children and adults with EM.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.