Evidence map›Paper›PMID 30214266›Full record

ReviewJournal of inflammation research2018

Fecal microbiota transplant - a new frontier in inflammatory bowel disease.

Tagore Sunkara, Prashanth Rawla, Andrew Ofosu, Vinaya Gaduputi

Open access · goldAbstract readReview
In one paragraph

Review in Journal of inflammation research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Inflammatory bowel disease andTherapeutic advances in gastroenterology · 2023
    Review
  8. Review
  9. Review of Literature onJournal of the ASEAN Federation of Endocrine Societies · 2022
    Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. The link among microbiota, epigenetics, and disease development.Environmental science and pollution research international · 2021
    Review
  15. Prevalence of an Intestinal ST40International journal of molecular sciences · 2020
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Tagore SunkaraDivision of Gastroenterology and Hepatology, The Brooklyn Hospital Center, Mount Sinai Health System, New York, NY, USA.
Prashanth RawlaDepartment of Internal Medicine, Sovah Health, Martinsville, VA, USA, rawlap@gmail.com.
Andrew OfosuDivision of Gastroenterology and Hepatology, The Brooklyn Hospital Center, Mount Sinai Health System, New York, NY, USA.
Vinaya GaduputiDivision of Gastroenterology, SBH Health System, Bronx, NY, USA.
Brooklyn Hospital Center · USNorthwell Health · USSovah Health Martinsville · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) is a chronic multifactorial disease that affects the gastrointestinal tract and results from an aberrant immune response toward luminal antigens in genetically susceptible people. Most of the current therapies for IBD focus on the management of the inflammation by using corticosteroids, immune modulators, and more recently, monoclonal antibodies (biological therapy). Although these therapies provide benefit in most cases, there are still a significant number of patients who do not respond or become refractory over time, suggesting the need for alternative therapeutic options. In the last decade, it has been recognized that "dysbiosis," an imbalanced gut microbiota, is a key element in IBD suggesting microbiome-based therapies as an attractive approach. Recently, fecal microbiota transplant (FMT) has been successfully used for the treatment of

Indexed as

Crohn’s diseasedysbiosisfecal microbiota transplantFMTIBDinflammatory bowel diseasemicrobiomeulcerative colitis

Identifiers

PMID30214266
PMCPMC6124474
OpenAlexW2889302878

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.