Evidence map›Paper›PMID 30214264›Full record

ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2018

Daily intake of

Susumu Yoshino, Riyo Awa, Yasuo Miyake, Ikuo Fukuhara, Hisao Sato, Toyotada Ashino, Shinpei Tomita, Hiroshige Kuwahara

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Nutrients · 2023
    Article
  10. Article
  11. Article
  12. Establishment of a Rapid Micropropagation System forPlants (Basel, Switzerland) · 2021
    Article
  13. Review
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Susumu YoshinoResearch and Development Division, Research Center, Maruzen Pharmaceuticals Co., Ltd., Hiroshima, Japan, s-yoshino@maruzenpcy.co.jp.
Riyo AwaResearch and Development Division, Research Center, Maruzen Pharmaceuticals Co., Ltd., Hiroshima, Japan, s-yoshino@maruzenpcy.co.jp.
Yasuo MiyakeResearch and Development Division, Research Center, Maruzen Pharmaceuticals Co., Ltd., Hiroshima, Japan, s-yoshino@maruzenpcy.co.jp.
Ikuo FukuharaFukuhara Clinic, Hokkaido, Japan.
Hisao SatoClinical Research Department, New Drug Research Center, Inc., Hokkaido, Japan.
Toyotada AshinoClinical Research Department, New Drug Research Center, Inc., Hokkaido, Japan.
Shinpei TomitaClinical Research Department, New Drug Research Center, Inc., Hokkaido, Japan.
Hiroshige KuwaharaResearch and Development Division, Research Center, Maruzen Pharmaceuticals Co., Ltd., Hiroshima, Japan, s-yoshino@maruzenpcy.co.jp.
Isuzu Advanced Engineering Center (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeObesity is a serious problem, which is now a worldwide health problem. MATERIALS AND

methodsA 12-week, single-center, randomized, double-blind, placebo-controlled clinical trial was conducted. Seventy-six subjects (males and females aged 20 to <65 years) with a body mass index ≥24 and <30 kg/m

resultsCompared with the placebo group, the active KPE group exhibited significant reduction in abdominal fat area (visceral, subcutaneous, and total fat) and triglyceride levels after 12 weeks. Subgroup analyses demonstrated a significant reduction in abdominal fat area and triglyceride levels in healthy subjects compared with the placebo group after 12 weeks. Neither group exhibited adverse events related to the test foods or clinically relevant abnormal changes in physical, biochemical, or hematologic parameters, or in urinalysis results and medical interview.

conclusionDaily ingestion of KPE safely reduces body fat, particularly abdominal fat, in Japanese overweight and preobese subjects.

Indexed as

healthy subjectsmetabolic disorderobesityrandomized clinical trialtriglyceridevisceral fat

Identifiers

PMID30214264
PMCPMC6120512
OpenAlexW2889114737

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.