Evidence map›Paper›PMID 30214257›Full record

ArticleInfection and drug resistance2018

Efficacy of intraventricular amikacin treatment in pan-resistant

Mariadelfina Molinaro, Paola Morelli, Manuela De Gregori, Simona De Gregori, Ilaria Giardini, Federica Tordato, Vincenzina Monzillo, Daria Pocaterra, Erminia Casari

Open access · goldAbstract readCase Reports
In one paragraph

Article in Infection and drug resistance, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Age of Antibiotic Resistance in MDR/XDR Clinical Pathogen ofPharmaceuticals (Basel, Switzerland) · 2023
    Review
  4. Detection of Antibiotic Resistance Genes inInfection and drug resistance · 2022
    Article
  5. Article
  6. Review
  7. Imipenem/Cilastatin/Relebactam Alone and in Combination againstAntimicrobial agents and chemotherapy · 2020
    Article
  8. Intrathecal Antibacterial and Antifungal Therapies.Clinical microbiology reviews · 2020
    Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Mariadelfina MolinaroClinical and Experimental Pharmacokinetics Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, m.molinaro@smatteo.pv.it.
Paola MorelliInfectious Diseases Unit, Hospital Health Direction, Humanitas Clinical and Research Center, Milan.
Manuela De GregoriClinical and Experimental Pharmacokinetics Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, m.molinaro@smatteo.pv.it.
Simona De GregoriClinical and Experimental Pharmacokinetics Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, m.molinaro@smatteo.pv.it.
Ilaria GiardiniClinical and Experimental Pharmacokinetics Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, m.molinaro@smatteo.pv.it.
Federica TordatoInfectious Diseases Unit, Hospital Health Direction, Humanitas Clinical and Research Center, Milan.
Vincenzina MonzilloMicrobiology and Virology Unit, Fondazione IRCCS Policlinico San Matteo.
Daria PocaterraInfectious Diseases Unit, Hospital Health Direction, Humanitas Clinical and Research Center, Milan.
Erminia CasariMicrobiology Unit, Analysis Laboratory, Humanitas Clinical and Research Center, Milan, Italy.
Humanitas University · ITPoliclinico San Matteo Fondazione · ITPain in Motion · BEUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe describe a case of pan-resistant CASE PRESENTATION: A female patient, who underwent surgery for a cavernous angioma, presented with meningitis. Cerebrospinal fluid culture revealed a multidrug-resistant

conclusionThe evaluation of the antibiotic concentration and the bactericidal activity in cerebrospinal fluid may contribute to the choice of the drug in cases of multidrug-resistant meningitis.

Indexed as

amikacinpan-resistant meningitisPseudomonas aeruginosa

Identifiers

PMID30214257
PMCPMC6128265
OpenAlexW2889381503

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.