Trial reportGenetics in medicine : official journal of the American College of Medical Genetics2019
Use of a novel computerized decision aid for aneuploidy screening: a randomized controlled trial.
Trial report in Genetics in medicine : official journal of the American College of Medical Genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07077707 (A Randomized Trial of Chatbot for Prenatal Genetic Counseling), which is not on this map. Cited by 11 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized Trial of Chatbot for Prenatal Genetic Counseling
Who cites it
11 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Decision aids for people facing health treatment or screening decisions.The Cochrane database of systematic reviews · 2024Pooled it
- Effectiveness of Interactive Digital Decision Aids in Prenatal Screening Decision-making: Systematic Review and Meta-analysis.Journal of medical Internet research · 2023Pooled it
- Use of Decision Support Tools to Empower Pregnant Women: Systematic Review.Journal of medical Internet research · 2020Pooled it
- Evaluating the reliability and clinical utility of artificial intelligence in first trimester prenatal screening and noninvasive prenatal testing.Scientific reports · 2025Article
- Healthcare professionals' experiences with expanded noninvasive prenatal screening: challenges and solutions.Journal of community genetics · 2025Article
- Clinical decision support systems for maternity care: a systematic review and meta-analysis.EClinicalMedicine · 2024Article
- Informal Prenatal Genetic Screening Education: What can you learn from Google and YouTube?Genetics in medicine open · 2024Article
- Multisite assessment of the impact of a prenatal testing educational App on patient knowledge and preparedness for prenatal testing decision making.Journal of community genetics · 2022Article
- Noninvasive prenatal testing: from aneuploidy to single genes.Human genetics · 2020Review
- Telehealth to provide prenatal genetics services: Feasibility and importance revealed during global pandemic.Prenatal diagnosis · 2020Article
- The Benefits of Introducing a Pregnancy Support Tool for Low-Income Women During Routine Obstetrics Care.Journal of primary care & community healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
purposeTo assess whether knowledge following use of a decision aid (DA) for aneuploidy screening and testing is inferior to knowledge in women who saw a genetic counselor (GC) only.
methodsThis is a randomized controlled noninferiority trial of pregnant women at ≤22 weeks. Women who were scheduled for GC were randomly allocated to use a DA before GC or to GC alone. The primary outcome was knowledge score, comparing women who had used the DA only to those who saw GC alone. Analysis was by intent to treat.
resultsBetween January and October 2017, 197 women were randomized, 105 to GC only and 92 to DA use before GC. Demographics and baseline knowledge were similar between groups. Mean knowledge score following DA use was not inferior to mean knowledge score following GC only (10.4 vs. 10.6, p = 0.306). Decisional conflict was similar following completion of the DA to following GC only, but was reduced following completion of both the DA and GC compared with GC only (0.22 vs. 1.74, p = 0.003).
conclusionKnowledge surrounding aneuploidy screening in women who used a DA was not inferior to knowledge in women who underwent GC. Use of the DA in addition to GC reduced decisional conflict.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.