Evidence map›Paper›PMID 30213862›Full record

ArticleThe Journal of biological chemistry2018

CD16a with oligomannose-type

Ganesh P Subedi, Adam W Barb

Abstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Article
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  6. Review
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  16. Review
  17. Review
  18. Article
  19. Role ofFrontiers in immunology · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ganesh P SubediFrom the Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology Iowa State University, Ames, Iowa 50011.
Adam W BarbFrom the Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology Iowa State University, Ames, Iowa 50011 abarb@iastate.edu.ORCID 0000-0003-3290-8649

Funding

Mechanism and engineering of IgG-based monoclonal antibody/receptor interactionsR01GM115489 · NIGMS · UNIVERSITY OF GEORGIA · PI BARB, ADAM WESLEY · 2015 to 2019
$1.4M
NIGMS NIH HHS R01 GM115489
6 · The paper itself

Abstract

Fc γ receptors (FcγRs) bind circulating IgG (IgG1) at the surface of leukocytes. Antibodies clustered at the surface of a targeted particle trigger a protective immune response through activating FcγRs. Three recent reports indicate that the composition of the asparagine-linked carbohydrate chains (

Indexed as

GlycosylationGPI-Linked ProteinsHEK293 CellsHumansImmunoglobulin Fc FragmentsImmunoglobulin GIn Vitro TechniquesOligosaccharidesPolysaccharidesProtein BindingReceptors, IgGFCGR3A protein, humanFCGR3B protein, humanGPI-Linked ProteinsImmunoglobulin Fc FragmentsImmunoglobulin GoligomannosideOligosaccharidesPolysaccharidesReceptors, IgGantibodyFc-gamma receptorFc receptorN-linked glycosylationpost-translational modification (PTM)

Identifiers

PMID30213862
PMCPMC6204906

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.