Evidence map›Paper›PMID 30213832›Full record

Trial reportHaematologica2019

Long-term follow up of pediatric Philadelphia positive acute lymphoblastic leukemia treated with the EsPhALL2004 study: high white blood cell count at diagnosis is the strongest prognostic factor.

Andrea Biondi, Gunnar Cario, Paola De Lorenzo, Anders Castor, Valentino Conter, Veronica Leoni, Virginie Gandemer, Rob Pieters, Jan Stary, Gabriele Escherich and 8 more

Abstract readClinical TrialLetter
In one paragraph

Trial report in Haematologica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. The Outcome of Pediatric Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: Experience from a Referral Center in South India.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2024
    Article
  8. Article
  9. Article
  10. Management of CNS Disease in Pediatric Acute Lymphoblastic Leukemia.Current hematologic malignancy reports · 2022
    Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Andrea BiondiPediatric Department, University of Milano-Bicocca, Fondazione MBBM/San Gerardo Hospital, Monza, Italy abiondi.unimib@gmail.com.
Gunnar CarioUniversity Medical Center, Christian-Albrechts-University Kiel, Germany.
Paola De LorenzoPediatric Department, University of Milano-Bicocca, Fondazione MBBM/San Gerardo Hospital, Monza, Italy.
Anders CastorDepartment of Pediatric Oncology, Skane University Hospital, Lund, Sweden.
Valentino ConterPediatric Department, University of Milano-Bicocca, Fondazione MBBM/San Gerardo Hospital, Monza, Italy.
Veronica LeoniPediatric Department, University of Milano-Bicocca, Fondazione MBBM/San Gerardo Hospital, Monza, Italy.
Virginie GandemerCHU Hôpital Sud, Rennes, France.
Rob PietersPrincess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.
Jan StaryUniversity Hospital Motol, Department of Pediatric Hematology and Oncology, Prague, Czech Republic.
Gabriele EscherichUniversity Medical Center Eppendorf, Clinic of Pediatric Hematology and Oncology, Hamburg, Germany.
Myriam CampbellChilean National Pediatric Oncology Group, PINDA, Hospital Roberto del Rio, Santiago, Chile.
Andishe AttarbaschiDepartment of Pediatric Hematology and Oncology, St. Anna Children's Hospital, Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Austria.
Chi-Kong LiThe Chinese University of Hong Kong, China.
Ajay VoraGreat Ormond Street Hospital for Children, London, UK.
Jutta BradtkeDepartment of Pediatric Hematology and Oncology, Justus Liebig University, Giessen, Germany.
Vaskar SahaDivision of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, UK.
Maria Grazia ValsecchiEsPhALL Trial Data Center, School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Martin SchrappeUniversity Medical Center, Christian-Albrechts-University Kiel, Germany.

Funding

DBT-Wellcome Trust India Alliance IA/M/12/1/500261Wellcome Trust
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Philadelphia ChromosomeAdolescentChildChild, PreschoolDisease-Free SurvivalFemaleFollow-Up StudiesHumansImatinib MesylateInfantLeukocyte CountMalePrecursor Cell Lymphoblastic Leukemia-LymphomaSurvival RateImatinib Mesylateacute lymphoblastic leukemia (ALL)Philadelphia chromosomepre-tyrosine kinase inhibitors (TKIs)

Identifiers

PMID30213832
PMCPMC6312020

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.