Evidence map›Paper›PMID 30213811›Full record

ArticleAJNR. American journal of neuroradiology2018

Quantification of Blood Velocity with 4D Digital Subtraction Angiography Using the Shifted Least-Squares Method.

Y Wu, G Shaughnessy, C A Hoffman, E L Oberstar, S Schafer, T Schubert, K L Falk, B J Davis, C A Mistretta, C M Strother and 1 more

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
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  7. Article
  8. Experimental study using phantom models of cerebral aneurysms and 4D-DSA to measure blood flow on 3D-color-coded images.Technology and health care : official journal of the European Society for Engineering and Medicine · 2024
    Article
  9. Article
  10. Flat-panel conebeam CT in the clinic: history and current state.Journal of medical imaging (Bellingham, Wash.) · 2021
    Article
  11. Virtual 2D angiography from four-dimensional digital subtraction angiography (4D-DSA): A feasibility study.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2021
    Article
  12. Article
  13. 4D-DSA: Development and Current Neurovascular Applications.AJNR. American journal of neuroradiology · 2021
    Review
  14. Optimizing the Quality of 4D-DSA Temporal Information.AJNR. American journal of neuroradiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 3 countries.

Y WuFrom the Departments of Medical Physics (Y.W., G.S., C.A.H., C.A.M., M.A.S.) yijingwu@wisc.edu.ORCID 0000-0002-7669-6919
G ShaughnessyFrom the Departments of Medical Physics (Y.W., G.S., C.A.H., C.A.M., M.A.S.).ORCID 0000-0001-6336-0343
C A HoffmanFrom the Departments of Medical Physics (Y.W., G.S., C.A.H., C.A.M., M.A.S.).ORCID 0000-0002-4158-4976
E L OberstarBiomedical Engineering (E.L.O., K.L.R., B.J.D.).ORCID 0000-0003-0049-2298
S SchaferSiemens Healthineers (S.S.), USA.ORCID 0000-0002-6989-5215
T SchubertRadiology (C.A.M., C.M.S., T.S.).ORCID 0000-0003-2373-5870
K L FalkBiomedical Engineering (E.L.O., K.L.R., B.J.D.).ORCID 0000-0001-7646-2541
B J DavisBiomedical Engineering (E.L.O., K.L.R., B.J.D.).ORCID 0000-0003-3542-2353
C A MistrettaFrom the Departments of Medical Physics (Y.W., G.S., C.A.H., C.A.M., M.A.S.).ORCID 0000-0002-6620-2831
C M StrotherRadiology (C.A.M., C.M.S., T.S.).ORCID 0000-0002-4235-8081
M A SpeidelFrom the Departments of Medical Physics (Y.W., G.S., C.A.H., C.A.M., M.A.S.).ORCID 0000-0003-3042-6769
Anna Needs Neuroblastoma Answers · USL-3 Communications (United States) · USFlorida Agricultural and Mechanical University · USI.R.C.C.S. Oasi Maria SS · ITSiemens Healthcare (United States) · USUniversity Hospital of Basel · CHUniversity of Wisconsin–Madison · US

Funding

U.W. RADIOLOGICAL SCIENCES TRAINING PROGRAMT32CA009206 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Bryan Patrick Bednarz · 1985 to 2026
$12.1M
4D DSA and 4D Fluoroscopy: Validation of Diagnostic and Therapeutic CapabilitiesR01HL116567 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI SPEIDEL, MICHAEL A, STROTHER, CHARLES MILTON · 2013 to 2018
$3.7M
NCI NIH HHS T32 CA009206NHLBI NIH HHS R01 HL116567
6 · The paper itself

Abstract

background and purpose4D-DSA provides time-resolved 3D-DSA volumes with high temporal and spatial resolutions. The purpose of this study is to investigate a shifted least squares method to estimate the blood velocity from the 4D DSA images. Quantitative validation was performed using a flow phantom with an ultrasonic flow probe as ground truth. Quantification of blood velocity in human internal carotid arteries was compared with measurements generated from 3D phase-contrast MR imaging. MATERIALS AND

methodsThe centerlines of selected vascular segments and the time concentration curves of each voxel along the centerlines were determined from the 4D-DSA dataset. The temporal shift required to achieve a minimum difference between any point and other points along the centerline of a segment was calculated. The temporal shift as a function of centerline point position was fit to a straight line to generate the velocity. The proposed shifted least-squares method was first validated using a flow phantom study. Blood velocities were also estimated in the 14 ICAs of human subjects who had both 4D-DSA and phase-contrast MR imaging studies. Linear regression and correlation analysis were performed on both the phantom study and clinical study, respectively.

resultsMean velocities of the flow phantom calculated from 4D-DSA matched very well with ultrasonic flow probe measurements with 11% relative root mean square error. Mean blood velocities of ICAs calculated from 4D-DSA correlated well with phase-contrast MR imaging measurements with Pearson correlation coefficient

conclusionsThe availability of 4D-DSA provides the opportunity to use the shifted least-squares method to estimate velocity in vessels within a 3D volume.

Indexed as

Least-Squares AnalysisAdultAngiography, Digital SubtractionBlood Flow VelocityCarotid Artery, InternalFemaleHumansImaging, Three-DimensionalMagnetic Resonance AngiographyMalePhantoms, Imaging

Identifiers

PMID30213811
PMCPMC6177311
OpenAlexW2891378987

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.