ArticleNeuroImage2019
Irritability uniquely predicts prefrontal cortex activation during preschool inhibitory control among all temperament domains: A LASSO approach.
Article in NeuroImage, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed.
- Bidirectional association between irritability and executive function in youth from late childhood to early adolescence: Between- and within-person effects.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2026Article
- Article
- Inhibition-related connectivity predicts irritability risk and resilience across early adolescence.Social cognitive and affective neuroscience · 2026Article
- Targeting inhibitory control in youth irritability: challenges and opportunities.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Review
- Neural Correlates of Inhibitory Control in Children: Evidence Using MRI and fNIRS.Brain topography · 2025Article
- fNIRS evidence of abnormal frontotemporal cortex activation and functional connectivity in depressed patients after stroke: neuromodulatory mechanisms from mild to moderate depression.Frontiers in neurology · 2025Article
- A network approach to the investigation of childhood irritability: probing frustration using social stimuli.Journal of child psychology and psychiatry, and allied disciplines · 2024Article
- An Expanded Conceptual Framework for Understanding Irritability in Childhood: The Role of Cognitive Control Processes.Clinical child and family psychology review · 2024Review
- Neuroimaging evidence of visual-vestibular interaction accounting for perceptual mislocalization induced by head rotation.Neurophotonics · 2024Article
- Irritability Moderates the Association between Cognitive Flexibility Task Performance and Related Prefrontal Cortex Activation in Young Children.Brain sciences · 2023Article
- Inhibitory Control in Early Childhood Aggression Subtypes: Mediation by Irritability.Child psychiatry and human development · 2023Article
- Cross-sectional and Longitudinal Associations of Anxiety and Irritability With Adolescents' Neural Responses to Cognitive Conflict.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2023Article
- Mediating effect of amygdala activity on response to fear vs. happiness in youth with significant levels of irritability and disruptive mood and behavior disorders.Frontiers in behavioral neuroscience · 2023Review
- Joint Consideration of Inhibitory Control and Irritability in Young Children: Contributions to Emergent Psychopathology.Research on child and adolescent psychopathology · 2022Article
- Resting-state functional connectivity does not predict individual differences in the effects of emotion on memory.Scientific reports · 2022Article
- Developmental patterning of irritability enhances prediction of psychopathology in preadolescence: Improving RDoC with developmental science.Journal of psychopathology and clinical science · 2022Article
- To snack or not to snack: Using fNIRS to link inhibitory control to functional connectivity in the toddler brain.Developmental science · 2022Article
- Executive functioning moderates neural mechanisms of irritability during reward processing in youth.Psychiatry research. Neuroimaging · 2022Article
- Differential associations of conduct disorder, callous-unemotional traits and irritability with outcome expectations and values regarding the consequences of aggression.Child and adolescent psychiatry and mental health · 2022Article
- Article
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Authors and funding
6 authors.
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Abstract
Temperament, defined as individual variation in the reactivity and regulation of emotional, motor, and attentional processes, has been shown to influence emotional and cognitive development during the preschool period (ages 4-5). While relationships between temperament and neural activity have been investigated previously, these have typically investigated individual temperament dimensions selected ad hoc. Since significant correlations exist between various temperament dimensions, it remains unclear whether these findings would replicate while analyzing all temperament dimensions simultaneously. Using functional near infrared spectroscopy (fNIRS), 4-5-year-old children (N = 118) were administered a Go/No-Go task to assess prefrontal cortex activation during inhibitory control. The relationship between PFC activation and all 15 temperament domains defined by the Children's Behavior Questionnaire (CBQ) was assessed using automatic feature selection via LASSO regression. Results indicate that only the Anger/Frustration dimension was predictive of activation during the inhibitory control task. These findings support previous work showing relationships between irritability and prefrontal activation during executive function and extend those findings by demonstrating the specificity of the activation-irritability relationship among temperament dimensions.
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