Evidence map›Paper›PMID 30213107›Full record

ArticleJournal of clinical medicine2018

Norepinephrine Administration Is Associated with Higher Mortality in Dialysis Requiring Acute Kidney Injury Patients with Septic Shock.

Ying-Ying Chen, Vin-Cent Wu, Wei-Chieh Huang, Yu-Chang Yeh, Mai-Szu Wu, Chiu-Ching Huang, Kwan-Dun Wu, Ji-Tseng Fang, Chih-Jen Wu, NSARF and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Ying-Ying ChenDivision of Nephrology, Department of Internal Medicine, MacKay Memorial Hospital, No. 92, Sec. 2, Zhongshan North Road, Taipei 10449, Taiwan. akochen45@hotmail.com.
Vin-Cent WuDivision of Nephrology, Department of Internal Medicine, National Taiwan University Hospital, No.7.Chung San South Road, Taipei 10002, Taiwan. q91421028@ntu.edu.tw.ORCID 0000-0001-7935-0991
Wei-Chieh HuangDivision of Cardiology, Department of Internal Medicine, Taipei Veterans General Hospital, No.201, Sec. 2, Shipai Road, Taipei 11217, Taiwan. hwcc0314@gmail.com.ORCID 0000-0003-3759-0131
Yu-Chang YehDepartment of Anesthesiology, National Taiwan University Hospital, No.7.Chung San South Road, Taipei 10002, Taiwan. tonyyeh@ntuh.gov.tw.
Mai-Szu WuDivision of Nephrology, Department of Internal Medicine, Taipei Medical University-Shuang Ho Hospital, No.291, Zhongzheng Road, Zhonghe District, New Taipei City 23561, Taiwan. maiszuwu@gmail.com.
Chiu-Ching HuangDivision of Nephrology, Department of Internal Medicine, China Medical University Hospital, No. 2, Yude Road, North District, Taichung 40447, Taiwan. cch@mail.cmuh.org.tw.
Kwan-Dun WuDivision of Nephrology, Department of Internal Medicine, National Taiwan University Hospital, No.7.Chung San South Road, Taipei 10002, Taiwan. kdwu@ntuh.gov.tw.
Ji-Tseng FangChang Gung University College of Medicine, Taoyuan, Taiwan; Kidney Research Center, Department of Nephrology, Chang Gung Memorial Hospital, 5. Fu-Hsing Street. Kuei Shan Hsiang, Taoyuan City 333, Taiwan. fangjits@cgmh.org.tw.
Chih-Jen WuDivision of Nephrology, Department of Internal Medicine, MacKay Memorial Hospital, No. 92, Sec. 2, Zhongshan North Road, Taipei 10449, Taiwan. yaliwcj@gmail.com.
NSARF
CAKS Group
National Taiwan University Hospital · TWChina Medical University · TWChang Gung University · TWNational Taiwan University · TWTaipei Medical University-Shuang Ho Hospital · TWTaipei Veterans General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Norepinephrine (NE) is the first-line vasoactive agent used in septic shock patients; however, the effect of norepinephrine on dialysis-required septic acute kidney injury (AKI-D) patients is uncertain. (2) Methods: To evaluate the impact of NE on 90-day mortality and renal recovery in septic AKI-D patients, we enrolled patients in intensive care units from 30 hospitals in Taiwan. (3) Results: 372 patients were enrolled and were divided into norepinephrine users and non-users. After adjustment by Inverse probability of treatment weighted (IPTW), there was no significant difference of baseline comorbidities between the two groups. NE users had significantly higher 90-day mortality rate and using NE is a strong predictor of 90-day mortality in the multivariate Cox regression (HR = 1.497,

Indexed as

acute kidney injurycritical caredialysisnorepinephrinesepsisvasoactive agents

Identifiers

PMID30213107
PMCPMC6162856
OpenAlexW2892227789

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.