Evidence map›Paper›PMID 30213089›Full record

ReviewInternational journal of molecular sciences2018

Microfluidic and Paper-Based Devices for Disease Detection and Diagnostic Research.

Joshua M Campbell, Joseph B Balhoff, Grant M Landwehr, Sharif M Rahman, Manibarathi Vaithiyanathan, Adam T Melvin

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 74 citations in OpenAlex.

  1. Review
  2. Beginning of the era of Organ-on-Chip models in osteoarthritis research.Journal of clinical orthopaedics and trauma · 2024
    Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
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  10. Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Microfluidic devices for detection of RNA viruses.Reviews in medical virology · 2021
    Review
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Joshua M CampbellCain Department of Chemical Engineering, Louisiana State University, Baton Rouge, LA 70803, USA. jcamp62@lsu.edu.
Joseph B BalhoffCain Department of Chemical Engineering, Louisiana State University, Baton Rouge, LA 70803, USA. jbalho1@lsu.edu.
Grant M LandwehrCain Department of Chemical Engineering, Louisiana State University, Baton Rouge, LA 70803, USA. glandw1@lsu.edu.
Sharif M RahmanCain Department of Chemical Engineering, Louisiana State University, Baton Rouge, LA 70803, USA. srahm12@lsu.edu.
Manibarathi VaithiyanathanCain Department of Chemical Engineering, Louisiana State University, Baton Rouge, LA 70803, USA. mvaith1@lsu.edu.
Adam T MelvinCain Department of Chemical Engineering, Louisiana State University, Baton Rouge, LA 70803, USA. melvin@lsu.edu.ORCID 0000-0003-0484-5871
Louisiana State University · US

Funding

Division of Chemical, Bioengineering, Environmental, and Transport Systems CBET1509713
6 · The paper itself

Abstract

Recent developments in microfluidic devices, nanoparticle chemistry, fluorescent microscopy, and biochemical techniques such as genetic identification and antibody capture have provided easier and more sensitive platforms for detecting and diagnosing diseases as well as providing new fundamental insight into disease progression. These advancements have led to the development of new technology and assays capable of easy and early detection of pathogenicity as well as the enhancement of the drug discovery and development pipeline. While some studies have focused on treatment, many of these technologies have found initial success in laboratories as a precursor for clinical applications. This review highlights the current and future progress of microfluidic techniques geared toward the timely and inexpensive diagnosis of disease including technologies aimed at high-throughput single cell analysis for drug development. It also summarizes novel microfluidic approaches to characterize fundamental cellular behavior and heterogeneity.

Indexed as

DimethylpolysiloxanesEquipment DesignHumansLab-On-A-Chip DevicesMicrofluidic Analytical TechniquesMicrofluidicsPoint-of-Care SystemsSingle-Cell AnalysisbaysilonDimethylpolysiloxaneshigh-throughput screeninglateral flow strip assaysLFSAsmicrofluidic devicesPDMSpoint of carepolydimethylsiloxanesingle cell analysisµPADs

Identifiers

PMID30213089
PMCPMC6164778
OpenAlexW2890893980

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.