Evidence map›Paper›PMID 30213059›Full record

ArticleInternational journal of molecular sciences2018

K⁺ and Rb⁺ Affinities of the Na,K-ATPase α₁ and α₂ Isozymes: An Application of ICP-MS for Quantification of Na⁺ Pump Kinetics in Myofibers.

Hesamedin Hakimjavadi, Cory A Stiner, Tatiana L Radzyukevich, Jerry B Lingrel, Natalie Norman, Julio A Landero Figueroa, Judith A Heiny

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hesamedin HakimjavadiDepartment of Pharmacology and Systems Physiology, University of Cincinnati, Cincinnati, OH 45229, USA. hakimjhn@mail.uc.edu.
Cory A StinerDepartment of Pharmacology and Systems Physiology, University of Cincinnati, Cincinnati, OH 45229, USA. stinerca@mail.uc.edu.
Tatiana L RadzyukevichDepartment of Pharmacology and Systems Physiology, University of Cincinnati, Cincinnati, OH 45229, USA. radzyutl@ucmail.uc.edu.
Jerry B LingrelDepartment of Molecular Genetics, Biochemistry and Microbiology, University of Cincinnati, Cincinnati, OH 45229, USA. lingrejb@ucmail.uc.edu.
Natalie NormanDepartment of Pharmacology and Systems Physiology, University of Cincinnati, Cincinnati, OH 45229, USA. normanne@mail.uc.edu.
Julio A Landero FigueroaDepartment of Pharmacology and Systems Physiology, University of Cincinnati, Cincinnati, OH 45229, USA. landerjo@ucmail.uc.edu.
Judith A HeinyDepartment of Pharmacology and Systems Physiology, University of Cincinnati, Cincinnati, OH 45229, USA. heinyja@ucmail.uc.edu.ORCID 0000-0001-8206-1111
University of Cincinnati · USAgilent Technologies (United States) · US

Funding

Isoform-specific roles of the Na,K-ATPase in skeletal muscleR01AR063710 · NIAMS · UNIVERSITY OF CINCINNATI · PI HEINY, JUDITH A, LINGREL, JERRY B · 2013 to 2017
$2.2M
NIAMS NIH HHS R01 AR063710NIH HHS RO1-AM-063710NIH HHS T32-GM-105526
6 · The paper itself

Abstract

The potassium affinities of Na,K-ATPase isozymes are important determinants of their physiological roles in skeletal muscle. This study measured the apparent K⁺ and Rb⁺ affinities of the Na,K-ATPase α₁ and α₂ isozymes in intact, dissociated myofibers obtained from WT and genetically altered mice (α₁

Indexed as

AnimalsBiological TransportIsoenzymesKineticsMaleMass SpectrometryMiceMice, Inbred C57BLMuscle, SkeletalPotassiumRubidiumSodiumSodium-Potassium-Exchanging ATPaseIsoenzymesPotassiumRubidiumSodiumSodium-Potassium-Exchanging ATPaseaffinityICP-MSisozymesmyofiberNa,K-ATPasepotassiumrubidiumskeletal muscle

Identifiers

PMID30213059
PMCPMC6165224
OpenAlexW2891149294

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.