SynthesisMedicine2018
Association between dietary carrot intake and breast cancer: A meta-analysis.
Synthesis in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Risk factors for breast cancer: an umbrella review of observational cohort studies and causal relationship analysis.Frontiers in oncology · 2025Pooled it
- Pooled it
- Microbial Biotransformation of the Sesquiterpene Carotol: Generation of Hydroxylated Metabolites with Potential Cytotoxic and Target-Specific Binding Activities.Biomolecules · 2025Article
- Carrot Juice Intake Affects the Cytokine and Chemokine Response in Human Blood after Ex Vivo Lipopolysaccharide-Induced Inflammation.Nutrients · 2023Article
- Article
- Root Vegetables-Composition, Health Effects, and Contaminants.International journal of environmental research and public health · 2022Review
- Association of Dietary Carrot/Carotene Intakes With Colorectal Cancer Incidence and Mortality in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial.Frontiers in nutrition · 2022Article
- Peeling Affects the Nutritional Properties of Carrot Genotypes.Foods (Basel, Switzerland) · 2021Article
- Association between Dietary Intake of Flavonoids and Cancer Recurrence among Breast Cancer Survivors.Nutrients · 2021Article
- Spinach consumption and nonalcoholic fatty liver disease among adults: a case-control study.BMC gastroenterology · 2021Article
- Association of Dietary Carrot Intake With Bladder Cancer Risk in a Prospective Cohort of 99,650 Individuals With 12.5 Years of Follow-Up.Frontiers in nutrition · 2021Article
- Bioactive CMolecules (Basel, Switzerland) · 2020Review
- Carrot Intake and Risk of Colorectal Cancer: A Prospective Cohort Study of 57,053 Danes.Nutrients · 2020Article
- Article
- Falcarindiol Purified From Carrots Leads to Elevated Levels of Lipid Droplets and Upregulation of Peroxisome Proliferator-Activated Receptor-γ Gene Expression in Cellular Models.Frontiers in pharmacology · 2020Article
- A Review of the Science of Colorful, Plant-Based Food and Practical Strategies for "Eating the Rainbow".Journal of nutrition and metabolism · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe aimed to estimate the association between dietary carrot intake and risk of breast cancer by conducting a meta-analysis of epidemiologic studies.
methodsRelevant studies were identified by searching databases through September 2017. We included studies that reported risk estimates with 95% confidence intervals for the association between dietary carrot intake and breast cancer risk. Random-effects models were used to calculate the summary risk estimates. Publication bias was estimated using Begg's funnel plot and Egger's regression asymmetry test.
resultsA total of 10 articles met the eligibility criteria and were included in the meta-analysis involving 13,747 cases. The combined odds ratios (ORs) of breast cancer for the highest compared with the lowest dietary carrot intake was 0.79 (95% CI: 0.68, 0.90), and a significant heterogeneity was observed. In the subgroup analyses separated by study design, the inverse associations were more pronounced in the case-control studies than in the cohort studies, while the associations did not significantly differ by geographical region, study quality, exposure assessment. Omission of any single study had little effect on the combined risk estimate.
conclusionThe overall current literatures suggested that dietary carrot intake was associated with decreased risk of breast cancer.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.