Evidence map›Paper›PMID 30212645›Full record

ArticleCell host & microbe2018

Mycobacterium tuberculosis Joyrides Alveolar Macrophages into the Pulmonary Interstitium.

Anu Goenka, Joshua Casulli, Tracy Hussell

Abstract readComment
PubMed Publisher
In one paragraph

Article in Cell host & microbe, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
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  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Anu GoenkaLydia Becker Institute of Infection and Immunology, University of Manchester, Manchester, UK.
Joshua CasulliLydia Becker Institute of Infection and Immunology, University of Manchester, Manchester, UK.
Tracy HussellLydia Becker Institute of Infection and Immunology, University of Manchester, Manchester, UK. Electronic address: tracy.hussell@manchester.ac.uk.

Funding

Medical Research Council MR/N001427/1Wellcome Trust 202865/Z/16/Z
6 · The paper itself

Abstract

Alveolar macrophages reside in the airway lumen, where they are thought to remain. However, in this issue of Cell Host & Microbe,Cohen et al. (2018) show that Mycobacterium tuberculosis may induce their translocation into the lung interstitium, potentially acting as a Trojan horse for bacillary dissemination to other phagocytes.

Indexed as

Mycobacterium tuberculosisHumansLungMacrophages, AlveolarPhagocytesTuberculosis, Pulmonary

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.