Evidence map›Paper›PMID 30212644›Full record

ArticleCell host & microbe2018

Blocking the Exit: CHIKV Neutralizing Antibodies Nip Viral Egress in the Bud.

Mary K McCarthy, Thomas E Morrison

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Cell host & microbe, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Mary K McCarthyDepartment of Immunology and Microbiology, University of Colorado School of Medicine, 12800 East 19th Avenue, Mail Stop 8333, Aurora, CO 80045, USA.
Thomas E MorrisonDepartment of Immunology and Microbiology, University of Colorado School of Medicine, 12800 East 19th Avenue, Mail Stop 8333, Aurora, CO 80045, USA. Electronic address: thomas.morrison@ucdenver.edu.
University of Colorado Denver · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neutralizing antibody responses are critical for protection from virus-induced disease. In this issue of Cell Host & Microbe, Jin et al. (2018) use advanced microscopy to elucidate mechanisms by which anti-CHIKV neutralizing monoclonal antibodies block viral egress and activate ADCC, suggesting such antibodies may be "triply functional."

Indexed as

Chikungunya virusAntibodies, NeutralizingAntibodies, ViralCell MembraneChikungunya FeverHumansAntibodies, NeutralizingAntibodies, Viral

Identifiers

PMID30212644
OpenAlexW2890814743

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.