Evidence map›Paper›PMID 30212597›Full record

SynthesisJournal of surgical oncology2018

Introducing fluorescence guided surgery into orthopedic oncology: A systematic review of candidate protein targets for Ewing sarcoma.

Sarah E Bosma, Pieter Baa van Driel, Pancras Cw Hogendoorn, Pd Sander Dijkstra, Cornelis Fm Sier

Open access · bronzeAbstract readSystematic Review
In one paragraph

Synthesis in Journal of surgical oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Role of immunotherapy in Ewing sarcoma.Journal for immunotherapy of cancer · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sarah E BosmaDepartment of Orthopedics, Leiden University Medical Center, The Netherlands.ORCID http://orcid.org/0000-0001-8070-3483
Pieter Baa van DrielDepartment of Orthopedics, Leiden University Medical Center, The Netherlands.
Pancras Cw HogendoornDepartment of Pathology, Leiden University Medical Center, The Netherlands.
Pd Sander DijkstraDepartment of Orthopedics, Leiden University Medical Center, The Netherlands.
Cornelis Fm SierDepartment of Surgery, Leiden University Medical Center, The Netherlands.
Leiden University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ewing sarcoma (ES), an aggressive bone and soft-tissue tumor, is treated with chemotherapy, radiotherapy, and surgery. Intra-operative distinction between healthy and tumorous tissue is of paramount importance but challenging, especially after chemotherapy and at complex anatomical locations. Near infrared (NIR) fluorescence-guided surgery (FGS) is able to facilitate the determination of tumor boundaries intra-operatively, improving complete resection and therefore survival. This review evaluates potential ES-specific proteins from the literature as targets for NIR FGS.

Indexed as

Biomarkers, TumorBone NeoplasmsHumansMonitoring, IntraoperativeOptical ImagingOrthopedic ProceduresSarcoma, EwingBiomarkers, TumorCD99cell surface targetsCXCR4Ewing sarcoma (ES)Image guided surgeryLINGO-1

Identifiers

PMID30212597
PMCPMC6220824
OpenAlexW2890682480

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.