Evidence map›Paper›PMID 30212580›Full record

ArticlePloS one2018

The Arctic charr (Salvelinus alpinus) genome and transcriptome assembly.

Kris A Christensen, Eric B Rondeau, David R Minkley, Jong S Leong, Cameron M Nugent, Roy G Danzmann, Moira M Ferguson, Agnieszka Stadnik, Robert H Devlin, Robin Muzzerall and 3 more

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 85 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Kris A ChristensenFisheries and Oceans Canada, Centre for Aquaculture and Environmental Research, West Vancouver, British Columbia, Canada.ORCID 0000-0003-0021-0326
Eric B RondeauFisheries and Oceans Canada, Centre for Aquaculture and Environmental Research, West Vancouver, British Columbia, Canada.ORCID 0000-0002-6680-7961
David R MinkleyUniversity of Victoria, Department of Biology, Victoria, British Columbia, Canada.
Jong S LeongUniversity of Victoria, Department of Biology, Victoria, British Columbia, Canada.
Cameron M NugentUniversity of Guelph, Department of Integrative Biology, Guelph, Ontario, Canada.
Roy G DanzmannUniversity of Guelph, Department of Integrative Biology, Guelph, Ontario, Canada.
Moira M FergusonUniversity of Guelph, Department of Integrative Biology, Guelph, Ontario, Canada.
Agnieszka StadnikSimon Fraser University, Molecular Biology and Biochemistry, Burnaby, British Columbia, Canada.
Robert H DevlinFisheries and Oceans Canada, Centre for Aquaculture and Environmental Research, West Vancouver, British Columbia, Canada.
Robin MuzzerallIcy Waters Ltd, Whitehorse, Yukon, Canada.
Michael EdwardsIcy Waters Ltd, Whitehorse, Yukon, Canada.
William S DavidsonSimon Fraser University, Molecular Biology and Biochemistry, Burnaby, British Columbia, Canada.
Ben F KoopUniversity of Victoria, Department of Biology, Victoria, British Columbia, Canada.
Fisheries and Oceans Canada · CAUniversity of Guelph · CAUniversity of Victoria · CAIcy Waters (Canada) · CASimon Fraser University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arctic charr have a circumpolar distribution, persevere under extreme environmental conditions, and reach ages unknown to most other salmonids. The Salvelinus genus is primarily composed of species with genomes that are structured more like the ancestral salmonid genome than most Oncorhynchus and Salmo species of sister genera. It is thought that this aspect of the genome may be important for local adaptation (due to increased recombination) and anadromy (the migration of fish from saltwater to freshwater). In this study, we describe the generation of a new genetic map, the sequencing and assembly of the Arctic charr genome (GenBank accession: GCF_002910315.2) using the newly created genetic map and a previous genetic map, and present several analyses of the Arctic charr genes and genome assembly. The newly generated genetic map consists of 8,574 unique genetic markers and is similar to previous genetic maps with the exception of three major structural differences. The N50, identified BUSCOs, repetitive DNA content, and total size of the Arctic charr assembled genome are all comparable to other assembled salmonid genomes. An analysis to identify orthologous genes revealed that a large number of orthologs could be identified between salmonids and many appear to have highly conserved gene expression profiles between species. Comparing orthologous gene expression profiles may give us a better insight into which genes are more likely to influence species specific phenotypes.

Indexed as

Genetic SpeciationGenomePhylogenyTranscriptomeAdaptation, PhysiologicalAnimalsArctic RegionsChromosome MappingCold TemperatureFemaleGenetic LinkageGenetic MarkersMaleOncorhynchus mykissPhenotypeSalmo salarGenetic Markers

Identifiers

PMID30212580
PMCPMC6136826
OpenAlexW2892375143

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.