Trial reportAmerican journal of physiology. Gastrointestinal and liver physiology2018
Associations between the gut microbiota and host responses to high altitude.
Trial report in American journal of physiology. Gastrointestinal and liver physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 91 citations in OpenAlex.
- Testosterone administration partially modulates gut microbiota responses to severe energy deficit.American journal of physiology. Endocrinology and metabolism · 2026Trial
- Effects of carbohydrate supplementation on aerobic exercise performance during acute high altitude exposure and after 22 days of acclimatization and energy deficit.Journal of the International Society of Sports Nutrition · 2020Trial
- Effects of Living High-Training Low and High on Body Composition and Metabolic Risk Markers in Overweight and Obese Females.BioMed research international · 2020Trial
- Acute stressor alters inter-species microbial competition for resistant starch-supplemented medium.Gut microbes · 2019Trial
- Effects of acute severe hypobaric hypoxia on gut-muscle axis in rats.Journal of physiology and biochemistry · 2026Article
- Review
- FMT and Bifidobacterium quadruple viable tablets supplementation modulate gut microbiota to ameliorate high-altitude exposure induced colonic injury.Frontiers in microbiology · 2026Article
- From mechanisms to therapeutics: molecular insights into gastrointestinal injury under high-altitude hypoxia.Frontiers in microbiology · 2026Review
- Gut-heart axis at high altitude: a dynamic mediator from hypoxic dysbiosis to adaptive cardioprotection.Frontiers in microbiology · 2026Review
- Hypoxia-Induced Gut-Brain Axis Remodeling and Insomnia: Mechanisms and Microbiota Adaptive Regulation from a Translational Perspective.Journal of inflammation research · 2026Review
- Body Composition, Microbiome and Physical Activity in Workers Under Intermittent Hypobaric Hypoxia.Nutrients · 2025Article
- Vaginal microecological characterization of women of childbearing age at different altitudes: a multi-omics exploration.BMC women's health · 2025Article
- The gut-kidney axis in high-altitude hypoxia: pathophysiological mechanisms and the central role of hypoxia inducible factor.Annals of medicine · 2025Review
- Alterations in the gastric and small intestinal microbiota of mice exposed to short-term and long-term hypoxia.Scientific reports · 2025Article
- High-altitude mountaineering induces adaptive gut microbiome shifts associated with dietary intake and performance markers.Scientific reports · 2025Article
- 'It takes a village': deciphering the role of the gut microbiome in the health and performance of military personnel.BMJ military health · 2025Review
- Gut Microbiota-Associated Metabolites Affected the Susceptibility to Heart Health Abnormality in Young Migrants at High-Altitude: Gut Microbiota and Associated Metabolites Impart Heart Health in Plateau.Exploration (Beijing, China) · 2025Article
- Lactobacillus johnsonii HL79 mitigate plateau environment-induced hippocampal dysfunction in mice.AMB Express · 2025Article
- Mechanisms and implications of the gut microbial modulation of intestinal metabolic processes.npj metabolic health and disease · 2025Review
- Human gut microbiota adaptation to high-altitude exposure: longitudinal analysis over acute and prolonged periods.Microbiology spectrum · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hypobaric hypoxia and dietary protein and fat intakes have been independently associated with an altered gastrointestinal (GI) environment and gut microbiota, but little is known regarding host-gut microbiota interactions at high altitude (HA) and the impact of diet macronutrient composition. This study aimed to determine the effect of dietary protein:fat ratio manipulation on the gut microbiota and GI barrier function during weight loss at high altitude (HA) and to identify associations between the gut microbiota and host responses to HA. Following sea-level (SL) testing, 17 healthy males were transported to HA (4,300 m) and randomly assigned to consume provided standard protein (SP; 1.1 g·kg
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.