Evidence map›Paper›PMID 30211981›Full record

ArticleStem cells translational medicine2018

Long-Term Engraftment (16 Years) of Myoblasts in a Human Infarcted Heart.

Marie Crahès, Marie-Cécile Bories, Jean-Thomas Vilquin, Jean-Pierre Marolleau, Michel Desnos, Jérôme Larghero, Gilles Soulat, Patrick Bruneval, Albert A Hagège, Philippe Menasché

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Stem cells translational medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 1 country.

Marie CrahèsDepartment of Pathology, Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France.
Marie-Cécile BoriesDepartment of Cardiovascular Surgery, Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France.
Jean-Thomas VilquinSorbonne Université, INSERM, CNRS, Center of Research in Myology, Institute of Myology, GH Pitié-Salpêtrière, Paris, France.
Jean-Pierre MarolleauCHU Amiens, Hematology and Cell Therapy Unit, Université Picardie Jules Verne, Amiens, France.
Michel DesnosUniversity Paris Descartes, Sorbonne Paris Cité, Paris, France.
Jérôme LargheroCell Therapy Unit, Assistance Publique-Hôpitaux de Paris, Hôpital Saint-Louis, Cell Therapy Unit, Paris, France.
Gilles SoulatUniversity Paris Descartes, Sorbonne Paris Cité, Paris, France.
Patrick BrunevalDepartment of Pathology, Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France.
Albert A HagègeUniversity Paris Descartes, Sorbonne Paris Cité, Paris, France.
Philippe MenaschéUniversity Paris Descartes, Sorbonne Paris Cité, Paris, France.ORCID 0000-0002-9845-4064
Assistance Publique – Hôpitaux de Paris · FRInserm · FRDélégation Paris 5 · FRHôpital Européen Georges-Pompidou · FRSorbonne Paris Cité · FRSorbonne Université · FRUniversité de Picardie Jules Verne · FRUniversité Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the case of a patient who had undergone injections of myoblasts in an infarct area 16 years before being referred for heart transplantation. The pathological examination of the explanted heart found persisting myotubes embedded in fibrosis. This finding supports the ability of myoblasts to survive in harsh environments, which can make them appealing candidates for transplantation in diseases requiring supply of new myogenic cells. Stem Cells Translational Medicine 2018;7:705-708.

Indexed as

AdultFibrosisHumansMaleMuscle Fibers, SkeletalMuscle, SkeletalMyoblasts, SkeletalMyocardial InfarctionMyocardiumMyosin Heavy ChainsTroponin TVentricular Function, LeftMyosin Heavy ChainsTroponin TClinical cell transplantationHeart failureLong-term follow-upMyoblasts

Identifiers

PMID30211981
PMCPMC6186271
OpenAlexW2891525961

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.