Evidence map›Paper›PMID 30211881›Full record

ArticleOptics letters2018

Multi-channel velocity multiplexing of single virus detection on an optofluidic chip.

Jennifer A Black, Vahid Ganjalizadeh, Joshua W Parks, Holger Schmidt

Abstract read
In one paragraph

Article in Optics letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. On-Chip Optical Detection of Viruses: A Review.Advanced photonics research · 2021
    Article
  6. Article
  7. Article
  8. Optofluidic Amplification-free Multiplex Detection of Viral Hemorrhagic Fevers.IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jennifer A Black
Vahid Ganjalizadeh
Joshua W Parks
Holger Schmidt

Funding

Multiplexed, Non-Amplified, Nucleic Acid-Based Identification of Multidrug Resistant Pathogens Using an Integrated Optofluidic PlatformR01AI116989 · NIAID · BRIGHAM YOUNG UNIVERSITY · PI HAWKINS, AARON R., PITT, WILLIAM G · 2015 to 2019
$5.4M
Hybrid integrated molecular analysis (HIMAS) for point-of-care diagnosticsR33AI100229 · NIAID · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI SCHMIDT, HOLGER · 2014 to 2016
$1.7M
NIAID NIH HHS R01 AI116989NIAID NIH HHS R33 AI100229
6 · The paper itself

Abstract

Liquid-core waveguide-based optofluidic devices have proven to be valuable tools for analysis of biological samples in fluid. They have enabled single bioparticle sensitivity while maintaining in-plane detection via light-induced fluorescence. The incorporation of multi-spot excitation with multimode interference (MMI) waveguides has enabled spatially and spectrally multiplexed detection of single viruses on an oxide-based optofluidic platform. Here, we introduce a new way of MMI-based multiplexing where multiple analysis channels are placed within a single multi-spot pattern. This stacked channel design enables both velocity and spectral multiplexing of single particles. The principle is demonstrated with differentiated detection of single H3N2 and H1N1 viruses on a polydimethylsiloxane platform.

Indexed as

Lab-On-A-Chip DevicesOptical DevicesInfluenza A Virus, H1N1 SubtypeInfluenza A Virus, H3N2 Subtype

Identifiers

PMID30211881
PMCPMC6309855

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.