Evidence map›Paper›PMID 30211556›Full record

ArticleThe journal of physical chemistry letters2018

Effects of Preferential Counterion Interactions on the Specificity of RNA Folding.

Joon Ho Roh, Duncan Kilburn, Reza Behrouzi, Wokyung Sung, R M Briber, Sarah A Woodson

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The journal of physical chemistry letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Joon Ho RohDepartment of Materials Science and Engineering , University of Maryland , College Park , Maryland 20742 , United States.ORCID http://orcid.org/0000-0002-5564-6779
Duncan KilburnT. C. Jenkins Department of Biophysics , Johns Hopkins University , Baltimore , Maryland 21218 , United States.
Reza BehrouziCell Biology , Harvard Medical School , Boston , Massachusetts 02115 , United States.
Wokyung SungDepartment of Physics , Pohang University of Science and Technology , Pohang 37673 , Republic of Korea.
R M BriberDepartment of Materials Science and Engineering , University of Maryland , College Park , Maryland 20742 , United States.
Sarah A WoodsonT. C. Jenkins Department of Biophysics , Johns Hopkins University , Baltimore , Maryland 21218 , United States.
Johns Hopkins University · USHarvard University · USPohang University of Science and Technology · KRUniversity of Maryland, College Park · US

Funding

TIME RESOLVED HYDROXYL RADICAL FOOTPRINTING OF RNAR01GM060819 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI WOODSON, SARAH A. · 1999 to 2019
$6.1M
Acquisition of GE Typhoon FLA9500 Variable Mode ImagerS10OD021567 · OD · JOHNS HOPKINS UNIVERSITY · PI MCCAFFERY, J. MICHAEL · 2017 to 2017
$147k
NIGMS NIH HHS R01 GM060819NIH HHS S10 OD021567
6 · The paper itself

Abstract

The real-time search for native RNA structure is essential for the operation of regulatory RNAs. We previously reported that a fraction of the Azoarcus ribozyme achieves a compact structure in less than a millisecond. To scrutinize the forces that drive initial folding steps, we used time-resolved SAXS to compare the folding dynamics of this ribozyme in thermodynamically isostable concentrations of different counterions. The results show that the size of the fast-folding population increases with the number of available counterions and correlates with the flexibility of initial RNA structures. Within 1 ms of folding, Mg

Indexed as

AzoarcusIonsKineticsMagnesiumNucleic Acid ConformationRNARNA, CatalyticRNA FoldingScattering, Small AngleThermodynamicsX-Ray DiffractionIonsMagnesiumRNARNA, Catalytic

Identifiers

PMID30211556
PMCPMC6351067
OpenAlexW2891669318

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.