SynthesisESC heart failure2018
The prognosis of mid-range ejection fraction heart failure: a systematic review and meta-analysis.
Synthesis in ESC heart failure, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Long-term mortality in heart failure with mid-range ejection fraction: systematic review and meta-analysis.ESC heart failure · 2022Pooled it
- Characteristics and long-term prognosis of patients with reduced, mid-range, and preserved ejection fraction: A systemic review and meta-analysis.Clinical cardiology · 2022Pooled it
- The prognosis of mid-range ejection fraction heart failure: a systematic review and meta-analysis.ESC heart failure · 2018Pooled it
- Clinical and Prognostic Impact of Hemodynamic Gain Index and Heart Hemodynamic Reserve in Heart Failure with Reduced and Mildly Reduced Ejection Fraction: A Multicenter Study.Diagnostics (Basel, Switzerland) · 2025Article
- Cardiovascular Magnetic Resonance in Survivors of Critical Illness: Cardiac Abnormalities Are Associated With Acute Kidney Injury.Journal of the American Heart Association · 2023Article
- Three and two-dimensional cardiac mechanics by speckle tracking are predictors of outcomes in chagas heart disease.Scientific reports · 2022Article
- Mortality from Heart Failure with Mid-Range Ejection Fraction.Arquivos brasileiros de cardiologia · 2022Article
- Association between self-management behaviour and quality of life in people with heart failure: a retrospective study.BMC cardiovascular disorders · 2022Article
- Baroreflex sensitivity but not microvolt T-wave alternans can predict major adverse cardiac events in ischemic heart failure.Cardiology journal · 2022Article
- Heart failure in type 2 diabetes: current perspectives on screening, diagnosis and management.Cardiovascular diabetology · 2021Review
- Characteristics and Temporal Trends in the Mortality of Different Heart Failure Phenotypes in Primary Care.Arquivos brasileiros de cardiologia · 2021Article
- Clinical and echocardiographic characteristics of patients with preserved versus mid-range ejection fraction.The international journal of cardiovascular imaging · 2021Article
- Treatment of Heart Failure with Mid-Range Ejection Fraction: What Is the Evidence.Journal of clinical medicine · 2021Review
- Heart Failure With Mid-range Ejection Fraction: A Distinctive Subtype or a Transitional Stage?Frontiers in cardiovascular medicine · 2021Review
- Article
- In-hospital and long-term mortality for acute heart failure: analysis at the time of admission to the emergency department.ESC heart failure · 2020Article
- Growth differentiation factor 15 as mortality predictor in heart failure patients with non-reduced ejection fraction.ESC heart failure · 2020Article
- Lower Rates of Heart Failure and All-Cause Hospitalizations During Pulmonary Artery Pressure-Guided Therapy for Ambulatory Heart Failure: One-Year Outcomes From the CardioMEMS Post-Approval Study.Circulation. Heart failure · 2020Article
- Rehospitalization burden and morbidity risk in patients with heart failure with mid-range ejection fraction.ESC heart failure · 2020Article
- Heart Failure With Mid-range or Recovered Ejection Fraction: Differential Determinants of Transition.Cardiac failure review · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsMid-range ejection fraction is a new entity of heart failure (HF) with undetermined prognosis till now. In our systematic review and meta-analysis, we assess the mortality and hospitalization rates in mid-range ejection fraction HF (HFmrEF) and compare them with those of reduced ejection fraction heart failure (HFrEF) and preserved ejection fraction HF (HFpEF). METHODS AND
resultsWe conducted our search in March 2018 in the following databases for relevant articles: PubMed, CENTRAL, Google Scholar, Web of Science, Scopus, NYAM, SIEGLE, GHL, VHL, and POPLINE. Our primary endpoint was assessing all-cause mortality and all-cause hospital re-admission rates in HFmrEF in comparison with HFrEF and HFpEF. Secondary endpoints were the possible causes of death and hospital re-admission. Twenty-five articles were included in our meta-analysis with a total of 606 762 adult cardiac patients. Our meta-analysis showed that HFmrEF had a lower rate of all-cause death than had HFrEF [relative risk (RR), 0.9; 95% confidence interval (CI), 0.85-0.94]. HFpEF showed a higher rate of cardiac mortality than did HFmrEF (RR, 1.09; 95% CI, 1.02-1.16). Also, HFrEF had a higher rate of non-cardiac mortality than had HFmrEF (RR, 1.31; 95% CI, 1.22-1.41).
conclusionsWe detected a significant difference between HFrEF and HFmrEF regarding all-cause death, and non-cardiac death, while HFpEF differed significantly from HFmrEF regarding cardiac death.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.