Evidence map›Paper›PMID 30211294›Full record

ArticleInternational journal of cardiology. Heart & vasculature2018

A study of association between platelet volume indices and ST elevation myocardial infarction.

Bhawani Yasassri Alvitigala, Mohammedu Aroos Fathima Azra, Darshana Udakara Kottahachchi, Madduma Mudiyanselage Priyamali Thusharika Jayasekera, Rajapaksha Arachchige Namal Kumarasiri Wijesinghe

Open access · goldAbstract read
In one paragraph

Article in International journal of cardiology. Heart & vasculature, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 25 citations in OpenAlex.

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  7. Analysis of Platelet Volume Indices and their utility in Acute Coronary Syndrome.Heart views : the official journal of the Gulf Heart Association
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Bhawani Yasassri AlvitigalaDepartment of Medical Laboratory Sciences, Faculty of Allied Health Sciences, General Sir John Kotelawala Defence University, Sri Lanka.
Mohammedu Aroos Fathima AzraDepartment of Medical Laboratory Sciences, Faculty of Allied Health Sciences, General Sir John Kotelawala Defence University, Sri Lanka.
Darshana Udakara KottahachchiDepartment of Medical Laboratory Sciences, Faculty of Allied Health Sciences, General Sir John Kotelawala Defence University, Sri Lanka.
Madduma Mudiyanselage Priyamali Thusharika JayasekeraDepartment of Clinical Sciences, Faculty of Medicine, General Sir John Kotelawala Defence University, Sri Lanka.
Rajapaksha Arachchige Namal Kumarasiri WijesingheDepartment of Clinical Sciences, Faculty of Medicine, General Sir John Kotelawala Defence University, Ratmalana, Sri Lanka.
General Sir John Kotelawala Defence University · LK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

INTRODUCTION AND

objectiveST elevation myocardial infarction (STEMI) is caused by formation of a thrombus at a ruptured atheromatous plaque. Larger platelets are enzymatically and metabolically more active and play a crucial role in thrombus formation. Our objective was to study the association between platelet volume indices (mean platelet volume (MPV) and platelet distribution width (PDW)) and STEMI.

methodsA hospital-based case control study to compare the platelet indices of 52 STEMI patients before commencing antiplatelet therapy and age and gender matched 52 controls who had no history of ischemic heart disease or antiplatelet therapy. Blood samples were collected to EDTA bottles and analyzed using Mindray BC 6800 automated analyzer.

resultsSTEMI patients had significantly increased mean MPV and PDW compared to the control group ((8.22 ± 0.99 fL vs 7.74 ± 0.69 fL,

conclusionIncreased MPV and PDW were found to have a significant association with STEMI and this test has the potential to be used as a preliminary test to identify high-risk patient for myocardial infarction.

Indexed as

Coronary artery diseaseMean platelet volumePlatelet distribution width

Identifiers

PMID30211294
PMCPMC6134176
OpenAlexW2891802171

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.