Evidence map›Paper›PMID 30211293›Full record

ArticleAlzheimer's & dementia (New York, N. Y.)2018

Neuroimaging and neuropsychological assessment of freezing of gait in Parkinson's disease.

Brent Bluett, Sarah Banks, Dietmar Cordes, Ece Bayram, Virendra Mishra, Jeffrey Cummings, Irene Litvan

Open access · goldAbstract read
In one paragraph

Article in Alzheimer's & dementia (New York, N. Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Comparison of FDOPA and FDG PET in Parkinson's Disease Patients with and without Freezing of Gait.Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India
    Article
  7. Topological reorganization of functional hubs in patients with Parkinson's disease with freezing of gait.Journal of neuroimaging : official journal of the American Society of Neuroimaging
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Brent BluettCleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV, USA.
Sarah BanksCleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV, USA.
Dietmar CordesCleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV, USA.
Ece BayramCleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV, USA.
Virendra MishraCleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV, USA.
Jeffrey CummingsCleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV, USA.
Irene LitvanDepartment of Neurosciences, University of California San Diego, La Jolla, CA, USA.
Lou Ruvo Brain Institute · USCleveland Clinic · USUniversity of California, San Diego · US

Funding

Renewal of Centers of Biomedical Research Excellence (COBRE) (Phase 2) CNTN - ResubmissionP20GM109025 · NIGMS · CLEVELAND CLINIC FOUNDATION · PI JESSICA KIRKLAND CALDWELL · 2015 to 2026
$22.8M
NIGMS NIH HHS P20 GM109025
6 · The paper itself

Abstract

introductionFreezing of gait (FOG) is a disabling phenomenon characterized by a brief, episodic absence or reduction of forward progression of the feet despite the intention to walk. It is a common cause of falls and mortality in cases with Parkinson's disease (PD). This article reviews neuropsychological and neuroimaging studies to date and introduces a new study of multimodal imaging and cognition in PD-FOG.

methodsA comprehensive literature search identified studies using neuropsychological evaluation and/or neuroimaging to evaluate PD-FOG.

resultsSeveral studies have evaluated PD-FOG, but few have combined neuropsychological and comprehensive neuroimaging and none longitudinally. DISCUSSION: A study using a combined approach longitudinally evaluating cognitive dysfunction and underlying neural networks in FOG is needed. We introduce the framework of a study which demonstrates the use of establishing an infrastructure for studying neurodegenerative disorders using the National Institutes of Health/National Institute of General Medical Science Center of Biomedical Research Excellence grant mechanism.

Indexed as

GaitNeuroimagingNeuropsychologyParkinson's disease

Identifiers

PMID30211293
PMCPMC6131985
OpenAlexW2808097530

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.