Evidence map›Paper›PMID 30211250›Full record

ArticleNeurophotonics2018

Atypical neural modulation in the right prefrontal cortex during an inhibitory task with eye gaze in autism spectrum disorder as revealed by functional near-infrared spectroscopy.

Takahiro Ikeda, Masahiro Hirai, Takeshi Sakurada, Yukifumi Monden, Tatsuya Tokuda, Masako Nagashima, Hideo Shimoizumi, Ippeita Dan, Takanori Yamagata

Open access · hybridAbstract read
In one paragraph

Article in Neurophotonics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Effects of LEGOBrain sciences · 2026
    Article
  2. Challenges in the Differential Classification of Individual Diagnoses from Co-Occurring Autism and ADHD Using Survey Data.... IEEE-EMBS International Conference on Biomedical and Health Informatics. IEEE-EMBS International Conference on Biomedical and Health Informatics · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Takahiro IkedaJichi Medical University, Department of Pediatrics, Shimotsuke, Japan.
Masahiro HiraiJichi Medical University, Center for Development of Advanced Medical Technology, Shimotsuke, Japan.
Takeshi SakuradaJichi Medical University, Center for Development of Advanced Medical Technology, Shimotsuke, Japan.
Yukifumi MondenJichi Medical University, Department of Pediatrics, Shimotsuke, Japan.
Tatsuya TokudaChuo University, Applied Cognitive Neuroscience Laboratory, Tokyo, Japan.
Masako NagashimaJichi Medical University, Department of Pediatrics, Shimotsuke, Japan.
Hideo ShimoizumiInternational University of Health and Welfare Rehabilitation Center, Nasu Institute for Developmental Disabilities, Otawara, Japan.
Ippeita DanChuo University, Applied Cognitive Neuroscience Laboratory, Tokyo, Japan.
Takanori YamagataJichi Medical University, Department of Pediatrics, Shimotsuke, Japan.
Jichi Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autism spectrum disorder (ASD) is characterized by impairment in social communication and the presence of restricted and repetitive behaviors and interests. Executive function impairment is reportedly partially responsible for these symptoms. Executive function includes planning, flexibility, and inhibitory control. Although planning and flexibility in ASD have been consistently reported as atypical, the atypicality of inhibitory control remains controversial. As most previous studies have used nonsocial stimuli to investigate inhibitory control in ASD, the effects of socially relevant information on the inhibitory control system in individuals with ASD remain unclear. Therefore, we developed a go/no-go task with gaze stimuli and measured hemodynamic responses in the right prefrontal cortex (PFC), involved in inhibitory processing in both typically developing (TD) children and children with ASD, using functional near-infrared spectroscopy. Direct gaze induced commission errors to similar extents in both groups. Contrary to the behavioral responses, neural activation in the right PFC was modulated by gaze direction only in the TD group. These findings suggest that the gaze-processing mechanisms in the prefrontal region may be affected by atypical gaze processing in other brain regions during an inhibitory control task with socially relevant information in ASD.

Indexed as

autism spectrum disordercortical hemodynamicsdorsolateral prefrontal cortexexecutive functiongaze directionoptical topography

Identifiers

PMID30211250
PMCPMC6123570
OpenAlexW2890643896

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.