Evidence map›Paper›PMID 30211248›Full record

ArticleOpen forum infectious diseases2018

Low Case Finding Among Men and Poor Viral Load Suppression Among Adolescents Are Impeding Namibia's Ability to Achieve UNAIDS 90-90-90 Targets.

Simon Agolory, Michael de Klerk, Andrew L Baughman, Souleymane Sawadogo, Nicholus Mutenda, Ndumbu Pentikainen, Naemi Shoopala, Adam Wolkon, Negussie Taffa, Gram Mutandi and 6 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05048472 (Implementation of Point of Care HIV Viral Load Monitoring to Improve Viral Load Suppression Among Children, Adolescents and Young People Living With HIV in East Africa), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05048472 nacompletednot on this mapstarted 2022, after this paper: background citation

Implementation of Point of Care HIV Viral Load Monitoring to Improve Viral Load Suppression Among Children, Adolescents and Young People Living With HIV in East Africa

TypeinterventionalSponsorMRC/UVRI and LSHTM Uganda Research UnitRan2022 to 2025Enrolled956ConditionsHIV, Viral Load, Point of Care MonitoringArmsAbbott HIV-1/2 VL Point of care Device
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 2 countries.

Simon AgoloryUS Centers for Disease Control and Prevention, Windhoek, Namibia.ORCID 0000-0001-5023-5754
Michael de KlerkUS Centers for Disease Control and Prevention, Windhoek, Namibia.
Andrew L BaughmanUS Centers for Disease Control and Prevention, Windhoek, Namibia.
Souleymane SawadogoUS Centers for Disease Control and Prevention, Windhoek, Namibia.
Nicholus MutendaNamibia Ministry of Health and Social Services, Windhoek, Namibia.
Ndumbu PentikainenNamibia Institute of Pathology, Windhoek, Namibia.
Naemi ShoopalaUS Centers for Disease Control and Prevention, Windhoek, Namibia.
Adam WolkonUS Centers for Disease Control and Prevention, Windhoek, Namibia.
Negussie TaffaUS Centers for Disease Control and Prevention, Windhoek, Namibia.
Gram MutandiUS Centers for Disease Control and Prevention, Windhoek, Namibia.
Anna JonasUS Centers for Disease Control and Prevention, Windhoek, Namibia.
Assegid Tassew MengistuNamibia Ministry of Health and Social Services, Windhoek, Namibia.
Edington DzinotyiweyiNamibia Ministry of Health and Social Services, Windhoek, Namibia.
Dimitri PrybylskiUS Centers for Disease Control and Prevention, Windhoek, Namibia.
Ndapewa HamunimeNamibia Ministry of Health and Social Services, Windhoek, Namibia.
Amy MedleyUS Centers for Disease Control and Prevention, Atlanta, Georgia.
Ministry of Health and Social Services · NACenters for Disease Control and Prevention · USNamibia Institute of Pathology · NA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn 2015, Namibia implemented an Acceleration Plan to address the high burden of HIV (13.0% adult prevalence and 216 311 people living with HIV [PLHIV]) and achieve the UNAIDS 90-90-90 targets by 2020. We provide an update on Namibia's overall progress toward achieving these targets and estimate the percent reduction in HIV incidence since 2010.

methodsData sources include the 2013 Namibia Demographic and Health Survey (2013 NDHS), the national electronic patient monitoring system, and laboratory data from the Namibian Institute of Pathology. These sources were used to estimate (1) the percentage of PLHIV who know their HIV status, (2) the percentage of PLHIV on antiretroviral therapy (ART), (3) the percentage of patients on ART with suppressed viral loads, and (4) the percent reduction in HIV incidence.

resultsIn the 2013 NDHS, knowledge of HIV status was higher among HIV-positive women 91.8% (95% confidence interval [CI], 89.4%-93.7%) than HIV-positive men 82.5% (95% CI, 78.1%-86.1%). At the end of 2016, an estimated 88.3% (95% CI, 86.3%-90.1%) of PLHIV knew their status, and 165 939 (76.7%) PLHIV were active on ART. The viral load suppression rate among those on ART was 87%, and it was highest among ≥20-year-olds (90%) and lowest among 15-19-year-olds (68%). HIV incidence has declined by 21% since 2010.

conclusionsWith 76.7% of PLHIV on ART and 87% of those on ART virally suppressed, Namibia is on track to achieve UNAIDS 90-90-90 targets by 2020. Innovative strategies are needed to improve HIV case identification among men and adherence to ART among youth.

Indexed as

90-90-90Antiretroviral therapyHIVHIV testingHIV viral loadNamibiaretention

Identifiers

PMID30211248
PMCPMC6128969
OpenAlexW2887233941

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.