Evidence map›Paper›PMID 30211233›Full record

ArticleJournal of immunology research2018

The Genetic Polymorphisms of NLRP3 Inflammasome Associated with T Helper Cells in Patients with Multiple Myeloma.

Xueyun Zhao, Mingqiang Hua, Shuxin Yan, Jie Yu, Fengjiao Han, Chaoqin Zhong, Ruiqing Wang, Chen Zhang, Ming Hou, Daoxin Ma

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Inflammasomes-New Contributors to Blood Diseases.International journal of molecular sciences · 2022
    Review
  8. Review
  9. Article
  10. P2RX7 at the Host-Pathogen Interface of Infectious Diseases.Microbiology and molecular biology reviews : MMBR · 2021
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Genetic variants ofAmerican journal of cancer research · 2020
    Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Xueyun ZhaoDepartment of Hematology, Qilu Hospital of Shandong University, Jinan, Shandong 250012, China.
Mingqiang HuaDepartment of Hematology, Qilu Hospital of Shandong University, Jinan, Shandong 250012, China.
Shuxin YanDepartment of Hematology, Qilu Hospital of Shandong University, Jinan, Shandong 250012, China.
Jie YuDepartment of Hematology, Qilu Hospital of Shandong University, Jinan, Shandong 250012, China.
Fengjiao HanDepartment of Hematology, Qilu Hospital of Shandong University, Jinan, Shandong 250012, China.
Chaoqin ZhongDepartment of Hematology, Qilu Hospital of Shandong University, Jinan, Shandong 250012, China.
Ruiqing WangDepartment of Hematology, Qilu Hospital of Shandong University, Jinan, Shandong 250012, China.
Chen ZhangDepartment of Hematology, Qilu Hospital of Shandong University, Jinan, Shandong 250012, China.
Ming HouDepartment of Hematology, Qilu Hospital of Shandong University, Jinan, Shandong 250012, China.
Daoxin MaDepartment of Hematology, Qilu Hospital of Shandong University, Jinan, Shandong 250012, China.ORCID 0000-0003-0664-8441
Qilu Hospital of Shandong University · CNBaotou Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pathogenesis of multiple myeloma (MM) remains unclear and the NLRP3 inflammasome has been more and more recognized in the progression of many diseases. To investigate the role of the NLRP3 inflammasome in MM, we determined the genetic polymorphisms and expression of NLRP3 inflammasome-related genes (IL-1

Indexed as

GenotypeAdultAgedAged, 80 and overAllelesCARD Signaling Adaptor ProteinsFemaleGenetic Predisposition to DiseaseHemoglobinsHumansInflammasomesInterleukin-18Interleukin-1betaLymphocyte CountMaleMiddle AgedCARD8 protein, humanCARD Signaling Adaptor ProteinsHemoglobinsInflammasomesInterleukin-18Interleukin-1betaNeoplasm ProteinsNF-kappa BNLR Family, Pyrin Domain-Containing 3 ProteinNLRP3 protein, human

Identifiers

PMID30211233
PMCPMC6126087
OpenAlexW2888095331

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.