Evidence map›Paper›PMID 30211220›Full record

ArticleBioMed research international2018

Changes in Liver Gene Expression and Plasma Concentration of Rbp4, Fetuin-A, and Fgf21 in Sprague-Dawley Rats Subjected to Different Dietary Interventions and Bariatric Surgery.

Dominika Stygar, Wojciech Pigłowski, Elżbieta Chełmecka, Bronisława Skrzep-Poloczek, Tomasz Sawczyn, Wojciech Garłowski, Jerzy Jochem, Konrad Wojciech Karcz

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Dominika StygarDepartment of Physiology, School of Medicine with Dentistry Division in Zabrze, Medical University of Silesia, Katowice, Poland.ORCID 0000-0001-8509-7507
Wojciech PigłowskiCenter for Translational Research and Molecular Biology of Cancer, Maria Skłodowska-Curie Institute, Oncology Center, Gliwice, Poland.
Elżbieta ChełmeckaDepartment of Statistics, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Medical University of Silesia, Katowice, Poland.
Bronisława Skrzep-PoloczekDepartment of Physiology, School of Medicine with Dentistry Division in Zabrze, Medical University of Silesia, Katowice, Poland.ORCID 0000-0002-3232-6377
Tomasz SawczynDepartment of Physiology, School of Medicine with Dentistry Division in Zabrze, Medical University of Silesia, Katowice, Poland.ORCID 0000-0001-8088-7681
Wojciech GarłowskiDepartment of Physiology, School of Medicine with Dentistry Division in Zabrze, Medical University of Silesia, Katowice, Poland.
Jerzy JochemDepartment of Physiology, School of Medicine with Dentistry Division in Zabrze, Medical University of Silesia, Katowice, Poland.
Konrad Wojciech KarczClinic of General, Visceral, Transplantation and Vascular Surgery, Hospital of the Ludwig Maximilian University, Munich, Germany.
Medical University of Silesia · PLLudwig-Maximilians-Universität München · DEThe Maria Sklodowska-Curie National Research Institute of Oncology · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo study the effect of duodenal-jejunal omega switch (DJOS) in combination with different dietary patterns on the retinol-binding protein (RBP4), fetuin-A, and fibroblast growth factor 21 (FGF21) plasma levels and their hepatic gene expressions in rats.

methodsA high-fat diet (HF) was given to 28 rats and 28 more were fed with a control diet (CD) for 2 months. After that, half of each group underwent either DJOS or SHAM surgery. For the next 2 months, half of the animals in each operation group were kept on the same diet as before and half of them had the diet changed. After 16 weeks of the experiment RBP4, fetuin-A, and FGF21 plasma levels as well as liver

resultsDJOS had a reductive impact on plasma levels of RBP4, fetuin-A, and FGF21 and

conclusionsThe efficiency of DJOS surgery, measured by hepatokines' plasma levels and their gene expressions in the liver, depends on the type of diet applied before and after surgery. Manipulation of dietary patterns can lead to marked improvements in metabolic profile after DJOS surgery.

Indexed as

Bariatric SurgeryDietalpha-2-HS-GlycoproteinAnimalsFibroblast Growth FactorsLiverMaleRatsRats, Sprague-DawleyRetinol-Binding Proteins, PlasmaTranscriptomealpha-2-HS-Glycoproteinfibroblast growth factor 21Fibroblast Growth FactorsRbp4 protein, ratRetinol-Binding Proteins, Plasma

Identifiers

PMID30211220
PMCPMC6126060
OpenAlexW2886237213

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.