Evidence map›Paper›PMID 30211165›Full record

ReviewFrontiers in medicine2018

Ultraviolet A1 Phototherapy for Fibrosing Conditions.

Thilo Gambichler, Lutz Schmitz

Registry-linked trialAbstract readReview
In one paragraph

Review in Frontiers in medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04922736 (Patient Reported Outcomes With UVA-1 Therapy for Treatment of Sclerosing Skin Diseases), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04922736 naactive not recruitingnot on this mapstarted 2021, after this paper: background citation

Patient Reported Outcomes With UVA-1 Therapy for Treatment of Sclerosing Skin Diseases

TypeinterventionalSponsorUniversity of UtahRan2021 to 2026Enrolled30ConditionsScleroderma, Systemic, Morphea, Graft Vs Host DiseaseArmsUVA-1 Phototherapy
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Evidence- and consensus-based guideline on lichen sclerosus.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2026
    Guideline
  2. Influence of ultraviolet A1 exposures on mood states: a randomized controlled study.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2024
    Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Keloids: a review of therapeutic management.International journal of dermatology · 2021
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Thilo GambichlerDepartment of Dermatology, Ruhr-University Bochum, Bochum, Germany.
Lutz SchmitzDepartment of Dermatology, Ruhr-University Bochum, Bochum, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this article we describe efficacy and safety aspects of ultraviolet A1 (UV-A1) phototherapy in fibrosing conditions. UV-A1 is a specific phototherapeutic modality that is defined by a selective spectral range (340-400 nm). UV-A1 includes distinct modes of action qualifying this method for therapy of a variety of conditions, in particular fibrosing skin diseases. Concerning efficacy of UV-A1 phototherapy in fibrosing conditions, the best evidence obtained from randomized controlled trials exists for localized scleroderma. Moreover, fibrosing disorders such as lichen sclerosus and graft-vs.-host disease can be treated successfully by means of UV- A1. Regarding the optimal dosage regimen medium-dose UV-A1 seems to be linked to the best benefit/risk ratio. Possible acute adverse events of UV-A1 phototherapy include erythema and provocation of photodermatoses. Skin ageing and skin cancer formation belong to the chronic adverse events that may occur after long-term UV-A1 phototherapy.

Indexed as

fibrosisirradiationphototherapysclerosisultraviolet A1UV-A1UVA1

Identifiers

PMID30211165
PMCPMC6119689

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.