Evidence map›Paper›PMID 30211158›Full record

ArticleFrontiers in bioengineering and biotechnology2018

Photocatalytic Activity of Polymer Nanoparticles Modulates Intracellular Calcium Dynamics and Reactive Oxygen Species in HEK-293 Cells.

Caterina Bossio, Ilaria Abdel Aziz, Gabriele Tullii, Elena Zucchetti, Doriana Debellis, Mattia Zangoli, Francesca Di Maria, Guglielmo Lanzani, Maria Rosa Antognazza

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 55 citations in OpenAlex.

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  10. Review
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  12. Intracellular CaFrontiers in physiology · 2023
    Review
  13. Review
  14. Article
  15. Article
  16. Recent advances in bioelectronics chemistry.Chemical Society reviews · 2020
    Review
  17. Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Caterina BossioCenter for Nano Science and Technology@PoliMi, Istituto Italiano di Tecnologia, Milan, Italy.
Ilaria Abdel AzizCenter for Nano Science and Technology@PoliMi, Istituto Italiano di Tecnologia, Milan, Italy.
Gabriele TulliiCenter for Nano Science and Technology@PoliMi, Istituto Italiano di Tecnologia, Milan, Italy.
Elena ZucchettiCenter for Nano Science and Technology@PoliMi, Istituto Italiano di Tecnologia, Milan, Italy.
Doriana DebellisElectron Microscopy Facility, Istituto Italiano di Tecnologia, Genova, Italy.
Mattia ZangoliInstitute for Organic Synthesis and Photoreactivity, CNR-ISOF, Bologna, Italy.
Francesca Di MariaInstitute for Organic Synthesis and Photoreactivity, CNR-ISOF, Bologna, Italy.
Guglielmo LanzaniCenter for Nano Science and Technology@PoliMi, Istituto Italiano di Tecnologia, Milan, Italy.
Maria Rosa AntognazzaCenter for Nano Science and Technology@PoliMi, Istituto Italiano di Tecnologia, Milan, Italy.
Italian Institute of Technology · ITCenter for Nano Science and Technology · ITInstitute of Organic Synthesis and Photoreactivity · ITPolitecnico di Milano · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Optical modulation of living cells activity by light-absorbing exogenous materials is gaining increasing interest, due to the possibility both to achieve high spatial and temporal resolution with a minimally invasive and reversible technique and to avoid the need of viral transfection with light-sensitive proteins. In this context, conjugated polymers represent ideal candidates for photo-transduction, due to their excellent optoelectronic and biocompatibility properties. In this work, we demonstrate that organic polymer nanoparticles, based on poly(3-hexylthiophene) conjugated polymer, establish a functional interaction with an

Indexed as

bio-organic electronicsCa2+ imagingcell optical stimulationconjugated polymerlightorganic semiconductorphotomodulationreactive oxygen species

Identifiers

PMID30211158
PMCPMC6119808
OpenAlexW2888361101

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.