Evidence map›Paper›PMID 30210709›Full record

ArticleAmerican journal of translational research2018

Association between circulating fibrocytes and angiographic coronary collaterals in patients with obstructive coronary artery disease.

Mary C Shields, Borna Mehrad, Ellen C Keeley

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mary C ShieldsDepartment of Medicine, Division of Cardiology, University of Virginia Charlottesville, Virginia.
Borna MehradThe Department of Medicine, University of Florida Gainesville, Florida.
Ellen C KeeleyThe Department of Medicine, University of Florida Gainesville, Florida.
University of Virginia · US

Funding

Modular design of multiscale models, with an application to the innate immune response to fungal respiratory pathogens.U01EB024501 · NIBIB · UNIVERSITY OF FLORIDA · PI LAUBENBACHER, REINHARD, MEHRAD, BORNA · 2017 to 2020
$2.9M
Fibrocytes in human pulmonary fibrosisR01HL098329 · NHLBI · UNIVERSITY OF VIRGINIA · PI MEHRAD, BORNA, ROSE, C EDWARD · 2011 to 2015
$2.7M
NIBIB NIH HHS U01 EB024501
6 · The paper itself

Abstract

Circulating fibrocytes are a population of bone marrow-derived progenitor cells that have been implicated in neovascularization. The recruitment of coronary artery collaterals, a form of neovascularization, is associated with improved outcomes in coronary artery disease. In this study, we tested the hypothesis that, in subjects with stable chronic coronary artery disease, the blood concentration of fibrocytes is associated with the presence of angiographic coronary collaterals. A total of 58 subjects with at least one epicardial coronary artery with ≥ 90% luminal stenosis were enrolled, among whom 26 (45%) had angiographic evidence of coronary collaterals. Subjects with collaterals had significantly elevated circulating concentrations of all examined subsets of activated fibrocytes, suggesting that there is a relationship between fibrocytes and coronary collateral recruitment.

Indexed as

circulating fibrocytesCoronary collaterals

Identifiers

PMID30210709
PMCPMC6129513
OpenAlexW3011773599

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.