ArticleAmerican journal of translational research2018
The neural regeneration effect of chitin biological absorbable tubes bridging sciatic nerve defects with sural nerve grafts.
Article in American journal of translational research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 20 citations in OpenAlex.
- Quercetin enhances survival and axonal regeneration of motoneurons after spinal root avulsion and reimplantation: experiments in a rat model of brachial plexus avulsion.Inflammation and regeneration · 2022Article
- Myelin-associated glycoprotein combined with chitin conduit inhibits painful neuroma formation after sciatic nerve transection.Neural regeneration research · 2022Article
- Cortical plasticity and nerve regeneration after peripheral nerve injury.Neural regeneration research · 2021Article
- Article
- Chitin and Chitosan Derivatives as Biomaterial Resources for Biological and Biomedical Applications.Molecules (Basel, Switzerland) · 2020Review
- Article
- Ipsilateral S2 nerve root transfer to pudendal nerve for restoration of external anal and urethral sphincter function: an anatomical study.Scientific reports · 2019Article
- Tissue engineering for the repair of peripheral nerve injury.Neural regeneration research · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the feasibility and efficacy of sural nerve grafts for repairing sciatic nerve defects using a chitin biological absorbable tube bridge.
methodsA sciatic nerve defect model in the rat was produced, and the sural nerve, cut from the ipsilateral leg, was used as a graft to repair the defect using chitin biological absorbable tube bridges. Then the number and morphology of regenerating myelinated fibers, nerve function index, nerve conduction velocity, and motor end plate and triceps surae muscle morphology were evaluated.
resultsThe number and morphology of regenerated fibers, nerve function index, nerve conduction velocity, and motor end plate and triceps surae muscle morphology were improved in rats in which the nerve defect was bridged with chitin biological absorbable tubes compared with rats in which the defect was repaired without tubes.
conclusionsThe findings suggest that using a sural nerve graft to repair sciatic nerve defects with chitin biological absorbable tubes bridge promotes structural and functional recovery, and improves end plate and muscle fiber morphology as well.
Indexed as
Identifiers
30210676PMC6129540W2980333925What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.