Evidence map›Paper›PMID 30210643›Full record

ArticleJournal of Cancer2018

Inhibition of Transient Receptor Potential Vanilloid 6 channel, elevated in human ovarian cancers, reduces tumour growth in a xenograft model.

Hui Xue, Yuzhuo Wang, Tyson J MacCormack, Tyler Lutes, Christopher Rice, Michelle Davey, Dominique Dugourd, T Toney Ilenchuk, John M Stewart

Open access · goldAbstract read
In one paragraph

Article in Journal of Cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 50 citations in OpenAlex.

  1. TRPV6-Mediated CaCancers · 2026
    Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Bidirectional Allosteric Coupling between PIPInternational journal of molecular sciences · 2024
    Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Ion Channels and Personalized Medicine in Gynecological Cancers.Pharmaceuticals (Basel, Switzerland) · 2023
    Review
  14. Article
  15. CaInternational journal of molecular sciences · 2022
    Review
  16. Article
  17. Review
  18. Review
  19. Targeting Ion Channels for Cancer Treatment: Current Progress and Future Challenges.Reviews of physiology, biochemistry and pharmacology · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Hui XueDepartment of Experimental Therapeutics, BC Cancer Agency, 675 West 10 th Avenue, Vancouver BC, Canada, V5Z 1L3.
Yuzhuo WangDepartment of Experimental Therapeutics, BC Cancer Agency, 675 West 10 th Avenue, Vancouver BC, Canada, V5Z 1L3.
Tyson J MacCormackDepartment of Chemistry and Biochemistry, Mount Allison University, Sackville, New Brunswick, Canada. E4L 1E4.
Tyler LutesDepartment of Chemistry and Biochemistry, Mount Allison University, Sackville, New Brunswick, Canada. E4L 1E4.
Christopher RiceSoricimed Biopharma Inc. 18 Botsford Street, Suite 201, Moncton, NB, Canada, E1C 4W7.
Michelle DaveySoricimed Biopharma Inc. 18 Botsford Street, Suite 201, Moncton, NB, Canada, E1C 4W7.
Dominique DugourdSoricimed Biopharma Inc. 18 Botsford Street, Suite 201, Moncton, NB, Canada, E1C 4W7.
T Toney IlenchukSoricimed Biopharma Inc. 18 Botsford Street, Suite 201, Moncton, NB, Canada, E1C 4W7.
John M StewartSoricimed Biopharma Inc. 18 Botsford Street, Suite 201, Moncton, NB, Canada, E1C 4W7.
BC Cancer Agency · CAMount Allison University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cancerovaryTRPV6

Identifiers

PMID30210643
PMCPMC6134823
OpenAlexW2886665265

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.