Evidence map›Paper›PMID 30210449›Full record

ArticleFrontiers in endocrinology2018

Prolactin Variants in Human Pituitaries and Pituitary Adenomas Identified With Two-Dimensional Gel Electrophoresis and Mass Spectrometry.

Shehua Qian, Yongmei Yang, Na Li, Tingting Cheng, Xiaowei Wang, Jianping Liu, Xuejun Li, Dominic M Desiderio, Xianquan Zhan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in endocrinology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Shehua QianKey Laboratory of Cancer Proteomics of Chinese Ministry of Health, Xiangya Hospital, Central South University, Changsha, China.
Yongmei YangGeriatric Department of Cadre's Ward, Baoji Traditional Chinese Medicine Hospital, Baoji, China.
Na LiKey Laboratory of Cancer Proteomics of Chinese Ministry of Health, Xiangya Hospital, Central South University, Changsha, China.
Tingting ChengKey Laboratory of Cancer Proteomics of Chinese Ministry of Health, Xiangya Hospital, Central South University, Changsha, China.
Xiaowei WangKey Laboratory of Cancer Proteomics of Chinese Ministry of Health, Xiangya Hospital, Central South University, Changsha, China.
Jianping LiuBio-Analytical Chemistry Research Laboratory, Modern Analytical Testing Center, Central South University, Changsha, China.
Xuejun LiDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha, China.
Dominic M DesiderioThe Charles B. Stout Neuroscience Mass Spectrometry Laboratory, Department of Neurology, College of Medicine, University of Tennessee Health Science Center, Memphis, TN, United States.
Xianquan ZhanKey Laboratory of Cancer Proteomics of Chinese Ministry of Health, Xiangya Hospital, Central South University, Changsha, China.
Xiangya Hospital Central South University · CNCentral South University · CNBaokang Hospital Affiliated to Tianjin University of Traditional Chinese Medicine · CNUniversity of Tennessee Health Science Center · US

Funding

Prefrontal-Accumbens Glutamate and Ethanol Escalation in Adolescent and Adult C57R01AA020610 · NIAAA · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI MELENDEZ, ROBERTO I · 2014 to 2018
$1.8M
NIAAA NIH HHS R01 AA020610
6 · The paper itself

Abstract

Human prolactin (hPRL) plays multiple roles in growth, metabolism, development, reproduction, and immunoregulation, which is an important protein synthesized in a pituitary. Two-dimensional gel electrophoresis (2DE) is an effective method in identity of protein variants for in-depth insight into functions of that protein. 2DE, 2DE-based PRL-immunoblot, mass spectrometry, and bioinformatics were used to analyze hPRL variants in human normal (control;

Indexed as

human pituitarymass spectrometrypost-translational modificationsprolactin variantsvariant pattern

Identifiers

PMID30210449
PMCPMC6121189
OpenAlexW2888899964

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.