ArticleFrontiers in cellular neuroscience2018
Counter-Balance Between Gli3 and miR-7 Is Required for Proper Morphogenesis and Size Control of the Mouse Brain.
Article in Frontiers in cellular neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 13 citations in OpenAlex.
- Article
- The history and function of a circular RNA.Nature communications · 2026Review
- The Principle of Cortical Development and Evolution.Neuroscience bulletin · 2025Review
- miR-7 controls glutamatergic transmission and neuronal connectivity in a Cdr1as-dependent manner.EMBO reports · 2024Article
- ERK signaling expands mammalian cortical radial glial cells and extends the neurogenic period.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Integrative Role of the SALL4 Gene: From Thalidomide Embryopathy to Genetic Defects of the Upper Limb, Internal Organs, Cerebral Midline, and Pituitary.Hormone research in paediatrics · 2024Review
- KIF5C deficiency causes abnormal cortical neuronal migration, dendritic branching, and spine morphology in mice.Pediatric research · 2022Article
- MiR-7 in Cancer Development.Biomedicines · 2021Review
- Unique and Specific mGenes · 2020Article
- MicroRNA-7: expression and function in brain physiological and pathological processes.Cell & bioscience · 2020Review
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
Brain morphogenesis requires precise regulation of multiple genes to control specification of distinct neural progenitors (NPs) and neuronal production. Dysregulation of these genes results in severe brain malformation such as macrocephaly and microcephaly. Despite studies of the effect of individual pathogenic genes, the counter-balance between multiple factors in controlling brain size remains unclear. Here we show that cortical deletion of Gli3 results in enlarged brain and folding structures in the cortical midline at the postnatal stage, which is mainly caused by the increased percentage of intermediate progenitors (IPs) and newborn neurons. In addition, dysregulation of neuronal migration also contributes to the folding defects in the cortical midline region. Knockdown of microRNA (miRNA) miR-7 can rescue abnormal brain morphology in
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