Evidence map›Paper›PMID 30210235›Full record

ArticleOncoTargets and therapy2018

Peripheral blood lymphocyte responses to cytomegalovirus seropositivity after allogeneic-hematopoietic stem cell transplantation.

Jiexin Zhang, Xian Chen, Guodong Rong, Ting Xu, Hong Zhao, Dan Chen, Lei Wu, Peijun Huang, Fang Wang

Open access · goldAbstract read
In one paragraph

Article in OncoTargets and therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jiexin ZhangDepartment of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, 210029, Nanjing, China, hpj63@163.com; wangfang@njmu.edu.cn.
Xian ChenDepartment of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, 210029, Nanjing, China, hpj63@163.com; wangfang@njmu.edu.cn.
Guodong RongDepartment of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, 210029, Nanjing, China, hpj63@163.com; wangfang@njmu.edu.cn.
Ting XuDepartment of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, 210029, Nanjing, China, hpj63@163.com; wangfang@njmu.edu.cn.
Hong ZhaoDepartment of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, 210029, Nanjing, China, hpj63@163.com; wangfang@njmu.edu.cn.
Dan ChenDepartment of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, 210029, Nanjing, China, hpj63@163.com; wangfang@njmu.edu.cn.
Lei WuDepartment of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, 210029, Nanjing, China, hpj63@163.com; wangfang@njmu.edu.cn.
Peijun HuangDepartment of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, 210029, Nanjing, China, hpj63@163.com; wangfang@njmu.edu.cn.
Fang WangDepartment of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, 210029, Nanjing, China, hpj63@163.com; wangfang@njmu.edu.cn.
Nanjing Medical University · CNJiangsu Province Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe main purpose of this study was to investigate the relationship among cytomegalovirus (CMV) viremia, peripheral immune cells alternations, and leukemia prognosis. PATIENTS AND

methodsWe studied 90 leukemia patients who underwent allogeneic hematopoietic stem cell transplantation (allo-HSCT) from 2008 to 2015. Their complete clinical laboratory data were collected until 1 year after transplantation.

resultsAll patients were serum CMV negative before allo-HSCT. After transplantation, the CMV reactivation group showed increased peripheral CD8

conclusionIn summary, CMV drives immune cell post-transplantation fluctuation, which also favors LFS of leukemia partly resulted from CD8

Indexed as

allo-HSCTCD8+ T cellscytomegalovirusleukemialeukemia-free survival

Identifiers

PMID30210235
PMCPMC6114473
OpenAlexW2888738564

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.