Evidence map›Paper›PMID 30210119›Full record

ArticleInternal medicine (Tokyo, Japan)2019

Fatal Chronic Active Epstein-Barr Virus Infection in a Rheumatoid Arthritis Patient Treated with Abatacept.

Akio Kawabe, Kazuhisa Nakano, Hiroko Miyata, Ryo Shibuya, Atsuji Matsuyama, Takaaki Ogoshi, Yoshiya Tanaka

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Akio KawabeThe First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan.
Kazuhisa NakanoThe First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan.
Hiroko MiyataThe First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan.
Ryo ShibuyaThe Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, Japan.
Atsuji MatsuyamaThe Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, Japan.
Takaaki OgoshiThe Department of Respiratory Medicine, School of Medicine, University of Occupational and Environmental Health, Japan.
Yoshiya TanakaThe First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan.
University of Occupational and Environmental Health Japan · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic active Epstein-Barr virus (CAEBV) T-cell type infection, systemic form, is characterized by persistent infectious mononucleosis-like symptoms, high Epstein-Barr virus (EBV) DNA levels in the peripheral blood, organ damage, and a poor prognosis. The association between CAEBV and rheumatoid arthritis (RA) is unclear. We report a case of fatal CAEBV T-cell type infection in an RA patient undergoing treatment with cytotoxic T-lymphocyte-associated antigen 4 immunoglobulin fusion protein (abatacept, ABT). CAEBV can rapidly worsen in RA patients receiving ABT. Thus, we should try to establish an early diagnosis in patients with CAEBV infection.

Indexed as

AbataceptArthritis, RheumatoidAsian PeopleChronic DiseaseEpstein-Barr Virus InfectionsFatal OutcomeFemaleHumansMiddle AgedAbataceptabataceptchronic active Epstein-Barr virus infectionrheumatoid arthritis

Identifiers

PMID30210119
PMCPMC6421150
OpenAlexW2892312476

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.