SynthesisThe Journal of international medical research2018
Association between serum level of advanced glycation end products and obstructive sleep apnea-hypopnea syndrome: a meta-analysis.
Synthesis in The Journal of international medical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.
- An umbrella review of systematic reviews and meta-analyses of observational investigations of obstructive sleep apnea and health outcomes.Sleep & breathing = Schlaf & Atmung · 2022Pooled it
- Chinese Guidelines for the Diagnosis and Surgical Treatment of Adult Obstructive Sleep Apnea (2024).World journal of otorhinolaryngology - head and neck surgery · 2026Article
- Evaluation of apelin, chemerin, leptin, resistin and vaspin levels in patients with obstructive sleep apnoea syndrome.Sleep & breathing = Schlaf & Atmung · 2026Article
- Association between sleep duration and cardiovascular risk: the EVasCu cross-sectional study.Frontiers in physiology · 2024Article
- Healthy Sleep Every Day Keeps the Doctor Away.International journal of environmental research and public health · 2022Review
- Possible Preventative/Rehabilitative Role of Gliflozins in OSA and T2DM. A Systematic Literature Review-Based Hypothesis.Advances in therapy · 2021Article
- Correlation between OSAHS and Early Peripheral Atherosclerosis Indices in Patients with Type 2 Diabetes Mellitus in China: A Cross-Sectional Inpatient Study.Journal of diabetes research · 2021Article
- The Associations Between Sleep Duration and Various Metabolic Health Indices Among Adults in the United States: A Multivariate Analysis of Variance (MANOVA) Using National Health and Nutrition Examination Survey (NHANES) 2021 to 2023 Dataset.Journal of primary care & community healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis meta-analysis was performed to assess the difference in the serum level of advanced glycation end products (AGEs) between patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) and controls.
methodsA systematic literature search was performed using PubMed, Elsevier, SCI, Wanfang, Weipu, and China National Knowledge Internet. Eligible studies that reported the serum AGE level in patients with OSAHS were identified by two reviewers. Review Manager version 5.2 (The Nordic Cochrane Centre, The Cochrane Collaboration, Copenhagen, Denmark) and R version 3.10 ( www.r-project.org ) were employed for data synthesis.
resultsFive studies involving 670 subjects were identified. The meta-analysis showed that the mean serum AGE level in the OSAHS group was 0.98 mmol/L higher than those in the control group (95% confidence interval, 0.69-1.27).
conclusionsThis meta-analysis showed that the serum AGE level was elevated in patients with OSAHS. This finding suggests that AGEs may play an important role in insulin resistance in OSAHS and serve as a biomarker for patients with OSAHS with a high risk of type 2 diabetes mellitus.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.