Evidence map›Paper›PMID 30209673›Full record

ReviewNeurochemical research2019

Alteration in NMDA Receptor Mediated Glutamatergic Neurotransmission in the Hippocampus During Senescence.

Ashok Kumar, Thomas C Foster

Abstract readReview
In one paragraph

Review in Neurochemical research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 68 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Review
  6. Janus Synapses as Modular Neurointerfaces.ACS applied materials & interfaces · 2026
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Unraveling the Connection: Pain and Endoplasmic Reticulum Stress.International journal of molecular sciences · 2024
    Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ashok KumarDepartment of Neuroscience, McKnight Brain Institute, University of Florida, PO Box 100244, Gainesville, FL, 32610-0244, USA. kash@ufl.edu.
Thomas C FosterDepartment of Neuroscience, McKnight Brain Institute, University of Florida, PO Box 100244, Gainesville, FL, 32610-0244, USA. foster1@ufl.edu.
University of Florida · US

Funding

University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI Peihua Qiu · 2007 to 2026
$22.8M
Estrogen and cognition over the lifespanR01AG037984 · NIA · UNIVERSITY OF FLORIDA · PI FOSTER, THOMAS C, KUMAR, ASHOK · 2011 to 2022
$3.3M
Signaling cascades and memory deficits during agingR37AG036800 · NIA · UNIVERSITY OF FLORIDA · PI FOSTER, THOMAS C · 2010 to 2018
$2.6M
MECHANISMS FOR ALTERED SYNAPTIC FUNCTION DURING AGINGR01AG014979 · NIA · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI FOSTER, THOMAS C · 1998 to 2011
$2.5M
Use of viral-vectors for studying effects of chronic inflammation on executive functionR01AG052258 · NIA · UNIVERSITY OF FLORIDA · PI FOSTER, THOMAS C · 2016 to 2020
$1.9M
Systemic inflammation in regulating the onset and progression of brain agingR01AG049711 · NIA · UNIVERSITY OF FLORIDA · PI FOSTER, THOMAS C · 2015 to 2019
$1.5M
National Institute on Aging R37AG036800National Institutes of Health RO1037984National Institutes of Health RO1052258National Institutes of Health RO11049711NIA NIH HHS P30 AG028740NIA NIH HHS R01 AG014979NIA NIH HHS R01 AG037984NIA NIH HHS R01 AG049711NIA NIH HHS R01 AG052258NIA NIH HHS R37 AG036800University of Florida Claude D. Pepper Older Americans Independence Center P30-AG028740
6 · The paper itself

Abstract

Glutamate is the primary excitatory neurotransmitter in neurons and glia. N-methyl-D-aspartate (NMDA), α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA), and kainate receptors are major ionotropic glutamate receptors. Glutamatergic neurotransmission is strongly linked with Ca

Indexed as

AgingAnimalsHippocampusHumansNeurogliaNeuronsNeurotransmitter AgentsReceptors, N-Methyl-D-AspartateSynaptic TransmissionNeurotransmitter AgentsReceptors, N-Methyl-D-AspartateAgingCalcium homeostasisGlutamatergic neurotransmissionHippocampusLTDLTPN-Methyl-D-aspartate receptorSynaptic function

Identifiers

PMID30209673
PMCPMC6374185
OpenAlexW2890613615

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.