Evidence map›Paper›PMID 30209232›Full record

ArticleProceedings. Biological sciences2018

Human-like Cmah inactivation in mice increases running endurance and decreases muscle fatigability: implications for human evolution.

Jonathan Okerblom, William Fletes, Hemal H Patel, Simon Schenk, Ajit Varki, Ellen C Breen

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings. Biological sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Mitochondrial respiration and HAmerican journal of physiology. Cell physiology · 2019
    Article
  15. Uniquely human CHRFAM7A gene increases the hematopoietic stem cell reservoir in mice and amplifies their inflammatory response.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Jonathan OkerblomCenter for Academic Research and Training in Anthropogeny (CARTA), University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
William FletesGlycobiology Research and Training Center (GRTC), University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
Hemal H PatelDepartment of Anesthesiology, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
Simon SchenkDepartment of Orthopedic Surgery, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
Ajit VarkiCenter for Academic Research and Training in Anthropogeny (CARTA), University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA a1varki@ucsd.edu.ORCID 0000-0002-2206-975X
Ellen C BreenDepartment of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
University of California San Diego · US

Funding

Tissue Imaging, Biochemistry and MorphologyP01HL091830 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WAGNER, PETER D · 2009 to 2013
$10.1M
BIOSYNTHESIS AND REGULATION OF SUBSTITUTED SIALIC ACIDSR01GM032373 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI VARKI, AJIT P · 1985 to 2022
$6.9M
NHLBI NIH HHS P01 HL091830NIGMS NIH HHS R01 GM032373
6 · The paper itself

Abstract

Compared to other primates, humans are exceptional long-distance runners, a feature that emerged in genus

Indexed as

RunningAnimalsMaleMiceMice, KnockoutMixed Function OxygenasesPhysical Conditioning, AnimalCMPacetylneuraminate monooxygenaseMixed Function Oxygenasesevolutionhumanhuntingrunning

Identifiers

PMID30209232
PMCPMC6158528
OpenAlexW2891742052

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.