Evidence map›Paper›PMID 30209183›Full record

ArticleJournal of clinical microbiology2018

Identifying Mixed Mycobacterium tuberculosis Infection and Laboratory Cross-Contamination during Mycobacterial Sequencing Programs.

David H Wyllie, Esther Robinson, Tim Peto, Derrick W Crook, Adebisi Ajileye, Priti Rathod, Rosemarie Allen, Lisa Jarrett, E Grace Smith, A Sarah Walker

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Microbial genomics · 2025
    Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Canada communicable disease report = Releve des maladies transmissibles au Canada · 2024
    Article
  11. Clinical and public health utility of Mycobacterium tuberculosis whole genome sequencing.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Microorganisms · 2020
    Review
  18. Article
  19. Towards standardisation: comparison of five whole genome sequencing (WGS) analysis pipelines for detection of epidemiologically linked tuberculosis cases.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

David H WyllieNuffield Department of Medicine, John Radcliffe Hospital, Oxford, United Kingdom david.wyllie@ndm.ox.ac.uk.ORCID 0000-0002-9155-6228
Esther RobinsonPublic Health England National Mycobacteriology Laboratory North and Central, Heartlands Hospital, Birmingham, United Kingdom.
Tim PetoNuffield Department of Medicine, John Radcliffe Hospital, Oxford, United Kingdom.
Derrick W CrookNuffield Department of Medicine, John Radcliffe Hospital, Oxford, United Kingdom.
Adebisi AjileyePublic Health England National Mycobacteriology Laboratory North and Central, Heartlands Hospital, Birmingham, United Kingdom.
Priti RathodPublic Health England National Mycobacteriology Laboratory North and Central, Heartlands Hospital, Birmingham, United Kingdom.
Rosemarie AllenPublic Health England National Mycobacteriology Laboratory North and Central, Heartlands Hospital, Birmingham, United Kingdom.
Lisa JarrettPublic Health England National Mycobacteriology Laboratory North and Central, Heartlands Hospital, Birmingham, United Kingdom.
E Grace SmithPublic Health England National Mycobacteriology Laboratory North and Central, Heartlands Hospital, Birmingham, United Kingdom.
A Sarah WalkerNuffield Department of Medicine, John Radcliffe Hospital, Oxford, United Kingdom.

Funding

Department of Health HICF-T5-358Wellcome TrustWellcome Trust WT098615/Z/12/Z
6 · The paper itself

Abstract

The detection of laboratory cross-contamination and mixed tuberculosis infections is an important goal of clinical mycobacteriology laboratories. The objective of this study was to develop a method to detect mixtures of different

Indexed as

Bacteriological TechniquesCoinfectionDiagnostic Tests, RoutineDNA, BacterialGenetic VariationHigh-Throughput Nucleotide SequencingHumansMycobacterium tuberculosisQuality ControlSequence Analysis, DNATuberculosisDNA, Bacterialcross-contaminationmixed infectionMycobacterium tuberculosisnext-generation sequencingquality control

Identifiers

PMID30209183
PMCPMC6204665

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.