ArticleJournal of virology2018
Susceptibility to Neutralization by Broadly Neutralizing Antibodies Generally Correlates with Infected Cell Binding for a Panel of Clade B HIV Reactivated from Latent Reservoirs.
Open access · bronzeAbstract read
In one paragraph
Article in Journal of virology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 32 citations in OpenAlex.
- Dual role of glycosylation in resistance to CD4-binding site broadly neutralizing antibodies.Journal of virology · 2026Article
- mGem: Opening Env and harnessing NK cell effector functions to eliminate HIV-1-infected cells.mBio · 2026Review
- Molecular parameters governing antibody FcγR signaling and effector functions in the context of HIV envelope.Cell reports · 2025Article
- Potent antibody-dependent cellular cytotoxicity of a V2-specific antibody is not sufficient for protection of macaques against SIV challenge.PLoS pathogens · 2024Article
- Antibody-dependent cellular cytotoxicity, infected cell binding and neutralization by antibodies to the SIV envelope glycoprotein.PLoS pathogens · 2023Article
- SARS-CoV-2 Portrayed against HIV: Contrary Viral Strategies in Similar Disguise.Microorganisms · 2021Review
- Mining HIV controllers for broad and functional antibodies to recognize and eliminate HIV-infected cells.Cell reports · 2021Article
- A clinical trial of non-invasive imaging with an anti-HIV antibody labelled with copper-64 in people living with HIV and uninfected controls.EBioMedicine · 2021Article
- Antibodies for Human Immunodeficiency Virus-1 Cure Strategies.The Journal of infectious diseases · 2021Review
- Characterizing the Relationship Between Neutralization Sensitivity andFrontiers in immunology · 2021Article
- TLR-Agonist Mediated Enhancement of Antibody-Dependent Effector Functions as Strategy For an HIV-1 Cure.Frontiers in immunology · 2021Review
- Relationships between Neutralization, Binding, and ADCC of Broadly Neutralizing Antibodies against Reservoir HIV.Journal of virology · 2020Article
- Autologous IgG antibodies block outgrowth of a substantial but variable fraction of viruses in the latent reservoir for HIV-1.Proceedings of the National Academy of Sciences of the United States of America · 2020Observational
- Roles of fragment crystallizable-mediated effector functions in broadly neutralizing antibody activity against HIV.Current opinion in HIV and AIDS · 2020Review
- HIV-Specific T Cells Can Be Generated against Non-escaped T Cell Epitopes with a GMP-Compliant Manufacturing Platform.Molecular therapy. Methods & clinical development · 2020Article
- V2-Specific Antibodies in HIV-1 Vaccine Research and Natural Infection: Controllers or Surrogate Markers.Vaccines · 2019Review
- Article
- Antibody responses to the HIV-1 envelope high mannose patch.Advances in immunology · 2019Review
- Knowns and Unknowns of Assaying Antibody-Dependent Cell-Mediated Cytotoxicity Against HIV-1.Frontiers in immunology · 2019Review
- Susceptibility to Neutralization by Broadly Neutralizing Antibodies Generally Correlates with Infected Cell Binding for a Panel of Clade B HIV Reactivated from Latent Reservoirs.Journal of virology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 6 institutions in 2 countries.
Yanqin Ren *Division of Infectious Diseases, Weill Cornell Medical College, New York, New York, USA.
Maria Korom *Department of Microbiology, Immunology, and Tropical Medicine, The George Washington University, Washington, DC, USA.
Ronald TruongDepartment of Microbiology, Immunology, and Tropical Medicine, The George Washington University, Washington, DC, USA.
Dora ChanDepartment of Microbiology, Immunology, and Tropical Medicine, The George Washington University, Washington, DC, USA.
Szu-Han HuangDivision of Infectious Diseases, Weill Cornell Medical College, New York, New York, USA.
Colin C KovacsMaple Leaf Medical Clinic, Toronto, Ontario, Canada.
Erika BenkoMaple Leaf Medical Clinic, Toronto, Ontario, Canada.
Jeffrey T SafritNantBioScience Inc./NantKwest LLC, Culver City, California, USA.
John LeeNantBioScience Inc./NantKwest LLC, Culver City, California, USA.
Hermes GarbánNantWorks, LLC, Culver City, California, USA.
Richard AppsDepartment of Microbiology, Immunology, and Tropical Medicine, The George Washington University, Washington, DC, USA.
Harris GoldsteinDepartment of Pediatrics, Albert Einstein College of Medicine, New York, New York, USA.
Rebecca M Lynch *Department of Microbiology, Immunology, and Tropical Medicine, The George Washington University, Washington, DC, USA rmlynch@email.gwu.edu rbjones@med.cornell.edu.
R Brad Jones *Division of Infectious Diseases, Weill Cornell Medical College, New York, New York, USA rmlynch@email.gwu.edu rbjones@med.cornell.edu.
George Washington University · USImmunityBio (United States) · USMaple Leaf Medical Clinic · CAAlbert Einstein College of Medicine · USCornell University · USNantWorks (United States) · US
Funding
SWG 2: Cure Research Scientific Working GroupP30AI117970 · NIAID · GEORGE WASHINGTON UNIVERSITY · PI Italo Mocchetti · 2015 to 2026
$29.6MBELIEVE: Bench to Bed Enhanced Lymphocyte Infusions to Engineer Viral EradicationUM1AI126617 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI JONES, R. BRAD, NIXON, DOUGLAS F · 2016 to 2020
$28.1MEFFECTS OF MACRONUTRIENT INTAKE ON BINGE EATINGF31MH012224 · NIMH · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI LATNER, JANET D · 1999 to 2001
$28kNIAID NIH HHS P30 AI117970NIAID NIH HHS UM1 AI126617NIMH NIH HHS F31 MH012224
Abstract
Efforts to cure human immunodeficiency virus (HIV) infection are obstructed by reservoirs of latently infected CD4
Indexed as
AdultAntibodies, MonoclonalAntibodies, NeutralizingAntibody-Dependent Cell CytotoxicityHIV-1HIV AntibodiesHIV Envelope Protein gp120HIV InfectionsHumansMaleMiddle AgedNeutralization TestsViremiaAntibodies, MonoclonalAntibodies, NeutralizingHIV AntibodiesHIV Envelope Protein gp120ADCCantibody-dependent cell cytotoxicitybNAbbroadly neutralizing antibodycorrelationhuman immunodeficiency virusinfected cell bindingneutralization
Identifiers
What OpenQuestion holds
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.