Evidence map›Paper›PMID 30209142›Full record

ArticleBMJ case reports2018

Invasive mediastinal aspergillosis presenting as superior vena cava syndrome in an immunocompetent patient.

Yasmin Rahim, Aisha Memon, Javaid Ahmed Khan

Abstract readCase Reports
In one paragraph

Article in BMJ case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. A young immunocompetent female with anterior mediastinal mass.Lung India : official organ of Indian Chest Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yasmin RahimDepartment of Pulmonology and Critical Care, Aga Khan University Hospital, Karachi, Pakistan.ORCID http://orcid.org/0000-0001-8746-3240
Aisha MemonDepartment of Histopathology, Aga Khan University Hospital, Karachi, Pakistan.
Javaid Ahmed KhanDepartment of Pulmonology and Critical Care, Aga Khan University Hospital, Karachi, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Invasive aspergillosis (IA) is a disease of the immunocompromised with a predilection for the lungs, although dissemination to all organs is possible. Its diagnosis remains a challenge due to the absence of specific clinical manifestations and laboratory findings. In most cases, diagnosis is eventually made via invasive methods. It carries with it a high mortality due to late diagnosis and delayed treatment. Here, we report a fascinating case of a young, otherwise healthy, immunocompetent patient that presented to us with superior vena cava syndrome and a mediastinal mass. It was anticipated that a malignancy would be found on further workup but, in fact, what was eventually discovered was a case of IA. Our report accentuates the significance of including IA as a differential while diagnosing a mediastinal mass in an immunocompetent host as patient outcome is determined by timely diagnosis and treatment.

Indexed as

AdultAntifungal AgentsAspergillosisAspergillus flavusDiagnosis, DifferentialHumansImmunocompetenceMaleMediastinal DiseasesMediastinumSuperior Vena Cava SyndromeAntifungal Agentslung cancer (oncology)Tb and other respiratory infections

Identifiers

PMID30209142
PMCPMC6144180

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.