ArticleBMJ (Clinical research ed.)2018
Compliance with requirement to report results on the EU Clinical Trials Register: cohort study and web resource.
Article in BMJ (Clinical research ed.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
79 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Time to publication for results of clinical trials.The Cochrane database of systematic reviews · 2024Pooled it
- Pooled it
- Results of trials assessing transarterial chemoembolization for treating hepatocellular carcinoma are critically underreported.European radiology · 2020Pooled it
- The insufficient publication of early-phase clinical trials in oncology.The oncologist · 2026Article
- Optimizing Development of Plain Language Summaries of Clinical Trial Results.Health literacy research and practice · 2026Article
- Barriers and enablers for publishing results of randomized trials: a cross-sectional survey of principal investigators in sub-Saharan Africa.Research integrity and peer review · 2026Article
- Non-Publication of Interventional Studies for Uveal Melanoma.Ocular oncology and pathology · 2026Article
- Observational
- Topic-specific living databases of clinical trials: A scoping review of public databases.Clinical trials (London, England) · 2026Article
- Rationale and Design of the Cancer Immunotherapy Evidence Living (CIEL) Library: A Continuously Updated Clinical Trial Database of Cancer Immunotherapies.Health science reports · 2026Article
- Adherence to legislation and recommendations to publicly post protocols and results of post-authorisation studies registered with European Medicines Agency: cross sectional study.BMJ (Clinical research ed.) · 2026Article
- Research waste in total knee arthroplasty studies: an observational study on registered trials.BMJ open · 2026Observational
- Human papillomavirus (HPV) vaccine clinical trials: A cross-sectional analysis of clinical trials registries.Human vaccines & immunotherapeutics · 2025Article
- Patterns of Oncological Clinical Trials in African Countries: A Scoping Review.Journal of cancer prevention · 2025Review
- Recent regulatory developments in EU Medical Device Regulation and their impact on biomaterials translation.Bioengineering & translational medicine · 2025Review
- Improving research transparency with individualized report cards: A feasibility study in clinical trials at a large university medical center.BMC medical research methodology · 2025Article
- Why too much biomedical research is often undeserving of the public's trust.Frontiers in genetics · 2025Article
- Exploring the publication gap in pediatric randomized clinical trials: completed vs. uncompleted pediatric clinical trials.Frontiers in medicine · 2025Article
- Human papillomavirus (HPV) trials: A cross-sectional analysis of clinical trials registries.Human vaccines & immunotherapeutics · 2024Article
- Publicly available continuously updated topic specific databases of randomised clinical trials: A scoping review.medRxiv : the preprint server for health sciences · 2024Article
19 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo ascertain compliance rates with the European Commission's requirement that all trials on the EU Clinical Trials Register (EUCTR) post results to the registry within 12 months of completion (final compliance date 21 December 2016); to identify features associated with non-compliance; to rank sponsors by compliance; and to build a tool for live ongoing audit of compliance.
designRetrospective cohort study.
settingEUCTR.
participants7274 of 11 531 trials listed as completed on EUCTR and where results could be established as due.
main outcome measurePublication of results on EUCTR.
resultsOf 7274 trials where results were due, 49.5% (95% confidence interval 48.4% to 50.7%) reported results. Trials with a commercial sponsor were substantially more likely to post results than those with a non-commercial sponsor (68.1%
conclusionsCompliance with the European Commission requirement for all trials to post results on to the EUCTR within 12 months of completion has been poor, with half of all trials non-compliant. EU registry data commonly contain inconsistencies that might prevent even regulators assessing compliance. Accessible and timely information on the compliance status of each individual trial and sponsor may help to improve reporting rates.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.