Evidence map›Paper›PMID 30208981›Full record

ReviewEpidemiology and psychiatric sciences2018

The neural basis of hostility-related dimensions in schizophrenia.

C Perlini, M Bellani, B Besteher, I Nenadić, P Brambilla

Open access · bronzeAbstract readReview
In one paragraph

Review in Epidemiology and psychiatric sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 2 countries.

C PerliniDepartment of Neurosciences, Biomedicine and Movement Sciences, Section of Clinical Psychology,University of Verona,Verona,Italy.ORCID http://orcid.org/0000-0002-4281-0920
M BellaniSection of Psychiatry,Azienda Ospedaliera Universitaria Integrata of Verona,Verona,Italy.
B BesteherDepartment of Psychiatry and Psychotherapy,Jena University Hospital,Jena,Germany.
I NenadićDepartment of Psychiatry and Psychotherapy,Philipps-University Marburg/Marburg University Hospital - UKGM,Marburg,Germany.
P BrambillaDepartment of Pathophysiology and Transplantation,University of Milan,Milan,Italy.
Azienda Ospedaliera Universitaria Integrata Verona · ITJena University Hospital · DEPhilipps University of Marburg · DEUniversity of Milan · ITUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hostility and related dimensions like anger, urgency, impulsivity and aggressiveness have been described in non-clinical populations and various serious mental illnesses including schizophrenia. Although representing a mental healthcare challenge, the investigation of such constructs is often limited by the presence of complex and multi-factorial causes and lack of agreement in their conceptualisation and measurement. In this review, we aim to clarify the anatomical basis of hostility-related dimensions in schizophrenia. Imaging studies suggest malfunctioning of a neural circuitry including amygdala, striatum, prefrontal cortex, anterior cingulate cortex, insula and hippocampus to modulate hostile thoughts and behaviours, at least in the subgroup of patients with schizophrenia who exhibit high levels of urgency, impulsivity and aggressiveness.

Indexed as

Brain MappingHostilitySchizophreniaSchizophrenic PsychologyAggressionAmygdalaBrainCerebral CortexGyrus CinguliHumansImpulsive BehaviorNeural PathwaysAggressivenesshostilityimpulsivityneuroimagingschizophreniaurgency

Identifiers

PMID30208981
PMCPMC6999008
OpenAlexW2891380480

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.