Evidence map›Paper›PMID 30208966›Full record

ArticleActa neuropathologica communications2018

Preserving prion strain identity upon replication of prions in vitro using recombinant prion protein.

Natallia Makarava, Regina Savtchenko, Peter Lasch, Michael Beekes, Ilia V Baskakov

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta neuropathologica communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Propagation of PrPCommunications biology · 2023
    Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Natallia MakaravaCenter for Biomedical Engineering and Technology, University of Maryland School of Medicine, 111 S. Penn St, Baltimore, MD, 21201, USA.
Regina SavtchenkoCenter for Biomedical Engineering and Technology, University of Maryland School of Medicine, 111 S. Penn St, Baltimore, MD, 21201, USA.
Peter LaschCentre for Biological Threats and Special Pathogens, Robert Koch-Institute, 13353, Berlin, Germany.
Michael BeekesCentre for Biological Threats and Special Pathogens, Robert Koch-Institute, 13353, Berlin, Germany.
Ilia V BaskakovCenter for Biomedical Engineering and Technology, University of Maryland School of Medicine, 111 S. Penn St, Baltimore, MD, 21201, USA. Baskakov@som.umaryland.edu.
University of Maryland, Baltimore · USRobert Koch Institute · DE

Funding

Self-Propagating Mechanism of Prion DiseasesR01NS045585 · NINDS · UNIVERSITY OF MD BIOTECHNOLOGY INSTITUTE · PI Ilia V Baskakov · 2003 to 2026
$9.6M
Role of prion protein sialylation in prion diseasesR01AI128925 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI BASKAKOV, ILIA V · 2017 to 2020
$3.2M
NIAID NIH HHS R01 AI128925NINDS NIH HHS R01 NS045585
6 · The paper itself

Abstract

Last decade witnessed an enormous progress in generating authentic infectious prions or PrP

Indexed as

AnimalsBrainCricetinaeDisease Transmission, InfectiousIn Vitro TechniquesPhosphatidylethanolaminesPoly APrion ProteinsProtein FoldingPrP 27-30 ProteinRecombinant ProteinsphosphatidylethanolaminePhosphatidylethanolaminesPoly ApolyadeninePrion ProteinsPrP 27-30 ProteinRecombinant ProteinsPrion diseasesPrionsPrion strainRecombinant prion proteinReplication cofactors

Identifiers

PMID30208966
PMCPMC6134792
OpenAlexW2891159651

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.