Evidence map›Paper›PMID 30208888›Full record

ArticleLipids in health and disease2018

The association between total bilirubin and serum triglyceride in both sexes in Chinese.

Xuemei Zhang, Zhaowei Meng, Xue Li, Ming Liu, Xiaojun Ren, Mei Zhu, Qing He, Qing Zhang, Kun Song, Qiyu Jia and 3 more

Open access · goldAbstract read
In one paragraph

Article in Lipids in health and disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Xuemei ZhangDepartment of Nuclear Medicine, Tianjin Medical University General Hospital, Anshan Road No. 154, Heping District, Tianjin, 300052, P.R, China.
Zhaowei MengDepartment of Nuclear Medicine, Tianjin Medical University General Hospital, Anshan Road No. 154, Heping District, Tianjin, 300052, P.R, China. jamesmencius@163.com.
Xue LiDepartment of Nuclear Medicine, Tianjin Medical University General Hospital, Anshan Road No. 154, Heping District, Tianjin, 300052, P.R, China.
Ming LiuDepartment of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin, P.R, China.
Xiaojun RenDepartment of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin, P.R, China.
Mei ZhuDepartment of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin, P.R, China.
Qing HeDepartment of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin, P.R, China.
Qing ZhangDepartment of Health Management, Tianjin Medical University General Hospital, Tianjin, P.R, China.
Kun SongDepartment of Health Management, Tianjin Medical University General Hospital, Tianjin, P.R, China.
Qiyu JiaDepartment of Health Management, Tianjin Medical University General Hospital, Tianjin, P.R, China.
Chunmei ZhangDepartment of Nuclear Medicine, Tianjin Medical University General Hospital, Anshan Road No. 154, Heping District, Tianjin, 300052, P.R, China.
Xiaoran WangDepartment of Nuclear Medicine, Tianjin Medical University General Hospital, Anshan Road No. 154, Heping District, Tianjin, 300052, P.R, China.
Xiangxiang LiuDepartment of Nuclear Medicine, Tianjin Medical University General Hospital, Anshan Road No. 154, Heping District, Tianjin, 300052, P.R, China.
Tianjin Medical University General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveDyslipidemia can cause some chronic diseases. Bilirubin is reported to have anti-inflammatory and anti-oxidant properties. We aimed to explore the relationship between triglyceride and total bilirubin (TB) in a large Chinese cohort.

methodsA total of 80,298 healthy Chinese (48,971 male, 31,327 female) enrolled in this cross-sectional study. Clinical data were collected from participants. Database was divided according to sex and age. The relationship between triglyceride and TB was analyzed by quartiles of TB. Levels of triglyceride were compared in different TB subgroups by one-way analysis of variance and independent sample's t-test. Crude and adjusted odds ratios of triglyceride for TB with 95% confidence intervals were analyzed by binary logistic regression models.

resultsOverall, men showed higher levels of TB and triglyceride than women. In people older than 60 years, women had higher triglyceride levels than men. Linear logistic regression analyses showed a negative relationship between triglyceride and TB in both genders. Men showed significantly higher overall incidence of high triglyceride than women. Men less than 60 years old showed a higher incidence of high triglyceride. For women older than 60 years, the incidence of high triglyceride was higher. However, high TB showed no protective effects on both genders from high TG in the binary logistic regression models. TB showed a detrimental effect on high TG in model 2 which included TB as a covariate. But that effect disappeared after other confounding factors were included.

conclusionsOur findings showed no association between TB and triglyceride in Chinese.

Indexed as

AdultAgedBilirubinChinaDyslipidemiasFemaleHumansLogistic ModelsMaleMiddle AgedRisk FactorsSex CharacteristicsTriglyceridesBilirubinTriglyceridesAgeGenderTotal bilirubin (TB)Triglyceride (TG)

Identifiers

PMID30208888
PMCPMC6136171
OpenAlexW2890300572

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.